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Glimepiride is an antidiabetic medication within the sulfonylurea class, primarily prescribed for the management of type 2 diabetes. [ 1 ] [ 2 ] It is regarded as a second-line option compared to metformin , due to metformin's well-established safety and efficacy. [ 1 ]
Higher risk of gastrointestinal side effects; Due to the risk of potentially fatal lactic acidosis, contraindicated in people with shock; with acute or chronic, moderate or severe kidney disease or at risk for impaired kidney function from intravenous dye; and with acute or chronic metabolic acidosis
Gliquidone is fully metabolized by the liver. Its metabolites are excreted virtually completely with bile (even with long-term administration), thus allowing the use of medication in diabetic patients with kidney disease and diabetic nephropathy. [2]
[2] [1] It contains the thiazolidinedione pioglitazone and the sulfonylurea glimepiride. [2] [1] It is taken by mouth. [2] [1] The most common side effects include upper respiratory tract infections (such as colds), hypoesthesia (reduced sense of touch), bone fractures, weight gain, dizziness, flatulence (gas) and edema (swelling). [1]
Less-common side effects can include excess air or gas in your stomach, burping, heartburn, indigestion, fast heartbeat, low blood sugar, low energy and fatigue, or even gallstones, Dr. Comite says.
Fiber has effects on intestinal operations, and by extension, on other tissues. For instance, adequate fiber intake seems to have an effect on vascular health. The mechanisms by which these effects happen are largely speculative at present. One effect of dietary fiber, apparently especially soluble fiber, has is to increase stool size and softness.
There are a few foods you may want to skip on Thanksgiving if you're taking a GLP-1 medication such as Ozempic, dietician Kylie Bensley, founder of the women’s nutrition company, Sulinu, tells ...
The cardioprotective effects of SGLT2 inhibitors have been attributed to the elevated ketone levels. [59] Gliflozins have been posited to exhibit protective effects on the heart, liver, kidneys, anti‐hyperlipidemic, anti‐atherosclerotic, anti‐obesity, anti‐neoplastic effects in in vitro, pre‐clinical, and
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