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Lab-on-a-chip technology can also be useful for the diagnosis and management of viral infections. In 2023, researchers developed a working prototype of an RT-LAMP lab-on-a-chip system called LoCKAmp, which provided results for SARS-CoV-2 tests within three minutes. [29] [30] Managing HIV infections is another area where lab-on-a-chips may be ...
Lab disk for protein structure analysis via small-angle X-ray scattering. The centrifugal micro-fluidic biochip or centrifugal micro-fluidic biodisk is a type of lab-on-a-chip technology, also known as lab-on-a-disc, that can be used to integrate processes such as separating, mixing, reaction and detecting molecules of nano-size in a single piece of platform, including a compact disk or DVD.
The Coastal and Marine Institute Laboratory (CMIL), formerly known as the Coastal Waters Laboratory, is an academic laboratory operated by the College of Sciences of San Diego State University (SDSU), in the Point Loma community of San Diego, California.
A microarray is a multiplex lab-on-a-chip. [1] Its purpose is to simultaneously detect the expression of thousands of biological interactions. It is a two-dimensional array on a solid substrate—usually a glass slide or silicon thin-film cell—that assays (tests) large amounts of biological material using high-throughput screening miniaturized, multiplexed and parallel processing and ...
PCR chips serve to miniaturize the reaction environment to achieve rapid heat transfer and fast mixing due to the larger surface-to-volume ratio and short diffusion distances. [39] The advantages of PCR chips include shorter thermal-cycling time, more uniform temperature which enhances yield, and portability for point-of-care applications. [ 39 ]
The main advantage of paper-based microfluidic devices over traditional microfluidics devices is their potential for use in the field rather than in a laboratory. [ 61 ] [ 62 ] Filter paper is advantageous in a field setting because it is capable of removing contaminants from the sample and preventing them from moving down the microchannel.
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Total analysis systems are designed to shrink the processes carried out in a laboratory to a chip-sized lab-on-a-chip. Due to this, it can be more cost-effective to carry out complex tests when considering chip technologies, sample sizes, and analysis time. Total analysis systems can also reduce the exposure of toxic chemicals for lab personnel.
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