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Citalopram, sold under the brand name Celexa among others, is an antidepressant of the selective serotonin reuptake inhibitor (SSRI) class. [7] [10] It is used to treat major depressive disorder, obsessive compulsive disorder, panic disorder, and social phobia. [7] The antidepressant effects may take one to four weeks to occur. [7]
For adults older than 64, SSRI's seem to reduce the risk of both suicidal behavior. [122] In 2016 a study criticized the effects of the FDA Black Box suicide warning inclusion in the prescription. The authors discussed the suicide rates might increase also as a consequence of the warning. [138]
More serious side effects may include suicidal thoughts in people up to the age of 24 years. [9] It is unclear if use during pregnancy or breastfeeding is safe. [ 10 ] Escitalopram is the ( S )- enantiomer of citalopram (which exists as a racemate ), hence the name es -citalopram.
Nephrotoxicity is toxicity in the kidneys. It is a poisonous effect of some substances, both toxic chemicals and medications, on kidney function. [1] There are various forms, [2] and some drugs may affect kidney function in more than one way. Nephrotoxins are substances displaying nephrotoxicity.
Bedroom side effects. Anorgasmia (difficulty experiencing climax) is a noted side effect of Lexapro. In women, clinical trials of escitalopram for depression found that roughly two to six percent ...
Citalopram (generic for Celexa) ... only cause ED and other intimate dysfunction issues in 30 percent of patients. Intimate side effects as a result of these medications are often referred to as ...
Serotonin. A serotonin reuptake inhibitor (SRI) is a type of drug which acts as a reuptake inhibitor of the neurotransmitter serotonin (5-hydroxytryptamine, or 5-HT) by blocking the action of the serotonin transporter (SERT).
But citalopram can also be viewed as a constrained analogue of paroxetine. [6] Figure 7 Chemical structures of (R)- and (S)-enantiomers of citalopram. Citalopram has the second most selectivity for SERT, no effects on NE or DA re-uptake and nor does it have affinity to other neuroreceptors. [6]