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Of the drugs that cause DIL, hydralazine has been found to cause a higher incidence. Hydralazine is a medication used to treat high blood pressure. Approximately 5% of the patients who have taken hydralazine over long periods of time and in high doses have shown DIL-like symptoms. [8] Many of the other drugs have a low to very low risk to ...
Prolonged treatment may cause a syndrome similar to lupus, which can become fatal if the symptoms are not noticed and drug treatment stopped. [13] Hydralazine is within the top three drugs that is known to induce systemic lupus and this adverse drug event is dose dependent yet significant.
DR4 is associated with extraarticular [2] rheumatoid arthritis, [3] hydralazine-induced female systemic lupus erythematosus, [4] pemphigoid gestationis, [5] pemphigus foliaceus, [6] obstructive hypertrophic cardiomyopathy, [7] IgA nephropathy, [8] 'shared syndrome'-systemic sclerosis/rheumatoid arthritis [9] and polymyalgia rheumatica.
Lupus is a chronic disease that can cause inflammation and pain in any part of the body. The disease impacts about 1.5 million Americans, but women are nine times more likely to develop lupus than ...
The Lupus Foundation of America estimates at least 1.5 million people are living with lupus in the United States. Symptoms may come and go, and can affect different organs in different people.
As usual, the U.K.'s National Institute for Health and Clinical Excellence -- or NICE -- isn't playing very nice. The agency in charge of determining what drugs are covered by the U.K.'s national ...
It therefore isn’t the only trigger that’s thought to be associated with lupus—other potential triggers that have been associated with SLE include cigarette smoking, viruses, bacteria, use of certain medications like procainamide, hydralazine, and isoniazid, as well as sex hormones, particularly estrogen, which might be partly why lupus ...
The oral drug, brepocitinib, did not meet the primary study goal of reduction in disease activity at week 52 in patients of SLE, in which the immune system that normally helps protect the body ...
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