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2-Fluoronitrobenzene is an organic compound with the formula FC 6 H 4 NO 2. It is one of three isomeric fluoronitrobenzenes. [1] A colorless liquid, it is prepared from 2-nitrochlorobenzene using the Halex process: O 2 NC 6 H 4 Cl + KF → O 2 NC 6 H 4 F + KCl
Side effects are analogous to those of ibuprofen. [2] It was derived from propionic acid by the research arm of Boots UK during the 1960s, a period which also included the discovery of ibuprofen, indometacin, diclofenac, naproxen, ketoprofen, and sulindac. [3] [4]: 34 It was patented in 1964 by Boots UK and approved for medical use in 1987. [5]
4-Fluoronitrobenzene can be hydrogenated to give 4-fluoroaniline, [3] which is a precursor to the fungicide fluoroimide and parafluorofentanyl. Owing to the presence of the electron withdrawing nitro group, the fluoride is a good leaving group in fluoronitrobenzenes. Thus reaction with phenoxide gives the mononitrodiphenylether. [4]
Flualprazolam is a tranquilizer of the triazolobenzodiazepine (TBZD) class, which are benzodiazepines (BZDs) fused with a triazole ring. It was first synthesised in 1976, [2] but was never marketed.
Clobazam was first synthesized in 1966 and first published in 1969. Clobazam was originally marketed as an anxioselective anxiolytic since 1970, [4] [5] and an anticonvulsant since 1984. [6] The primary drug-development goal was to provide greater anxiolytic, anti-obsessive efficacy with fewer benzodiazepine-related side effects. [4]
Less-common side effects can include excess air or gas in your stomach, burping, heartburn, indigestion, fast heartbeat, low blood sugar, low energy and fatigue, or even gallstones, Dr. Comite says.
[4] Common side effects of fludrocortisone include high blood pressure, swelling, heart failure, and low blood potassium. [3] Other serious side effects can include low immune-system function, cataracts, muscle weakness, and mood changes. [3] Whether use of fludrocortisone during pregnancy is safe for the fetus is unknown. [5]
Some reports in a review supported by Novo Nordisk suggested that semaglutide may decrease the risk of kidney disease over the long term. But there were also a few reports of folks taking GLP-1s ...