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  2. Skull bossing - Wikipedia

    en.wikipedia.org/wiki/Skull_bossing

    Frontal bossing is the development of an unusually pronounced forehead which may also be associated with a heavier than normal brow ridge. It is caused by enlargement of the frontal bone , often in conjunction with abnormal enlargement of other facial bones , skull , mandible , and bones of the hands and feet.

  3. Paget's disease of bone - Wikipedia

    en.wikipedia.org/wiki/Paget's_disease_of_bone

    Heart failure is a rare, reported consequence of severe Paget's disease (i.e. more than 40% skeletal involvement). The abnormal bone formation is associated with recruitment of abnormal blood vessels, forcing the cardiovascular system to work harder (pump more blood) to ensure adequate circulation.

  4. Craniosynostosis - Wikipedia

    en.wikipedia.org/wiki/Craniosynostosis

    Compensatory growth occurs forward at the coronal suture and backward at the lambdoid suture giving respectively a prominent forehead, called frontal bossing, and a prominent back portion of the head, called coning. [10] [11] This is the most common form of craniosynostosis. [13]

  5. Kagami-Ogata Syndrome - Wikipedia

    en.wikipedia.org/wiki/Kagami-Ogata_Syndrome

    Kagami-Ogata syndrome is a rare genetic disease that is caused by mutations on Maternal chromosome 14 or by paternal UPD(14). [1] The main signs of this disease are: polyhydramnios, narrow bell-shaped thorax, coat-hanger-like ribs, abdominal wall defect, enlarged placenta. [2]

  6. Acromegaly - Wikipedia

    en.wikipedia.org/wiki/Acromegaly

    Soft tissue swelling of internal organs, notably the heart with the attendant weakening of its muscularity, and the kidneys, also the vocal cords resulting in a characteristic thick, deep voice and slowing of speech; Generalized expansion of the skull at the fontanelle; Pronounced brow protrusion, often with ocular distension (frontal bossing)

  7. Periostitis - Wikipedia

    en.wikipedia.org/wiki/Periostitis

    Acute periostitis is due to infection, characterized by diffuse formation of pus, severe pain, and constitutional symptoms, and usually results in necrosis.It can be caused by excessive physical activity as well, as in the case of medial tibial stress syndrome (also referred to as tibial periostalgia, soleus periostalgia, or shin splints).

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