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Pegfilgrastim, sold under the brand name Neulasta among others, is a PEGylated form of the recombinant human granulocyte colony-stimulating factor (GCSF) analog filgrastim. [19] It serves to stimulate the production of white blood cells ( neutrophils ).
The most common side effects are fatigue, nausea, diarrhea, bone pain, headache, fever, anemia, rash, myalgia, arthralgia, and back pain. [ 4 ] Eflapegrastim was approved for medical use in the United States in September 2022.
Common side effects include fever, cough, chest pain, joint pain, vomiting, and hair loss. [19] Severe side effects include splenic rupture and allergic reactions. [19] It is unclear if use in pregnancy is safe for the baby. [19] Filgrastim is a recombinant form of the naturally occurring granulocyte colony-stimulating factor (G-CSF). [19]
A number of diseases can cause bone pain, including the following: Endocrine, such as hyperparathyroidism, osteoporosis, kidney failure. [7]Gastrointestinal or systemic, such as celiac disease and non-celiac gluten sensitivity (both often occur without obvious digestive symptoms), inflammatory bowel disease (including Crohn's disease and ulcerative colitis).
Efbemalenograstim alfa is an immunostimulant/colony stimulating factor that belongs to the class of hematopoietic growth factors (granulocyte colony stimulating factor; G CSF) which increase the production and differentiation of mature and functionally active neutrophils from bone marrow precursor cells. [2]
It falls under the umbrella of two other medication classes: analgesics (pain relievers) and antipyretics (fever reducers), says Dr. Anureet Walia, MD, a pain management specialist with UI Health ...
Sandoz, a division of Novartis AG (NVS), announced on Tuesday that the European Commission authorized its Ziextenzo for commercialization in Europe. Ziextenzo is a biosimilar product to Amgen's ...
Atrophic non-union results in re-absorption and rounding of bone ends [6] due to inadequate blood supply and excessive mobility of the bone ends. [4] Mal-union: healing occurs but the healed bone has 'angular deformity, translation, or rotational alignment that requires surgical correction'. This is most common in long bones such as the femur. [10]