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n/a Ensembl ENSG00000181143 n/a UniProt Q8WXI7 n/a RefSeq (mRNA) NM_024690 NM_001401501 n/a RefSeq (protein) NP_078966 n/a Location (UCSC) Chr 19: 8.85 – 8.98 Mb n/a PubMed search n/a Wikidata View/Edit Human Mucin-16 (MUC-16) also known as Ovarian cancer-related tumor marker CA125 is a protein that in humans is encoded by the MUC16 gene. MUC-16 is a member of the mucin family glycoproteins ...
CA-125 levels in premenopausal women over 200 U/mL may indicate ovarian cancer, as may any elevation in CA-125 above 35 U/mL in post-menopausal women. CA-125 levels are not accurate in early stage ovarian cancer, as half of stage I ovarian cancer patients have a normal CA-125 level.
CA-125: Mainly ovarian cancer, [13] but may also be elevated in for example endometrial cancer, fallopian tube cancer, lung cancer, breast cancer and gastrointestinal cancer. [14] Calcitonin: medullary thyroid carcinoma [15] Calretinin: mesothelioma, sex cord-gonadal stromal tumor, adrenocortical carcinoma, synovial sarcoma [9] Carcinoembryonic ...
The presence of an ovarian fibroma can cause ovarian torsion in some cases. Diagnosis ... In a series of 16 patients, 5 (28%) showed elevated levels of CA-125. [1]
The tumor marker CA-125 is frequently elevated in endometrial cancer and can be used to monitor response to treatment, particularly in serous cell cancer or advanced disease. [ 32 ] [ 44 ] [ 82 ] Periodic MRIs or CT scans may be recommended in advanced disease and women with a history of endometrial cancer should receive more frequent pelvic ...
The CA-125 marker in children and adolescents can be frequently elevated even in absence of malignancy and conservative management should be considered. Polycystic ovarian syndrome involves the development of multiple small cysts in both ovaries due to an elevated ratio of leutenizing hormone to follicle stimulating hormone , typically more ...
Elevated CEA levels should return to normal after successful surgical removal of the tumor and can be used in follow up, especially of colorectal cancers. [15] CEA elevation is known to be affected by multiple factors. It varies inversely with tumor grade; well-differentiated tumors secrete more CEA.
CA-125 is elevated. Clinical diagnosis can be made based on history and imaging, while the gold standard for definitive diagnosis remains Video-assisted thoracoscopic surgery, or VATS, which allows not only the visualization of the lesion, but also surgical treatment via cauterization of the ectopic endometrial tissue. Special staining under a ...