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One scientific review of 60 studies published in 2020 found that valerian root could help people fall asleep faster, reduce how often they wake up at night, and improve their sleep quality, but ...
A small study with six human subjects found that valerenic acid peaked in concentration after about an hour and had an average half-life of 1.1 +/- 0.6 hours after oral ingestion of a commercially available valerian root supplement. [8] A later study from the same lab done with sixteen older women found similar values. [3]
Valerian (Valeriana officinalis, Caprifoliaceae) is a perennial flowering plant native to Eurasia. It produces a catnip-like response in cats.. Crude extract of valerian root may have sedative and anxiolytic effects, and is commonly sold in dietary supplement capsules to promote sleep, but clinical evidence that it is effective for this purpose is weak or inconclusive.
Valerian: garden valerian, garden heliotrope, all-heal Valeriana officinalis "drowsiness, GI upset, headache, palpitations, insomnia", [3] oversedation, overstimulation [16] Vasambu sweet flag Acorus calamus: Vomiting and nausea [22] Yohimbe: yohimbine Pausinystalia johimbe: rapid heart rate, hypertension, hypotension, heart problems, death [4]
A natural supplement that puts you to sleep? At the same time, the supplement world is notorious for inflated claims, so the hype around melatonin and valerian makes me more than a little skeptical.
Isovaleramide is a constituent of valerian root. In humans, it acts as a mild anxiolytic at lower doses and as a mild sedative at higher dosages. [ 1 ] Isovaleramide has been shown to be non- cytotoxic and does not act as a CNS stimulant .
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