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Sotagliflozin (Inpefa) is a dual SGLT1/SGLT2 inhibitor approved by the US Food and Drug Administration (FDA) in May 2023, to reduce the risk of cardiovascular death, hospitalization for heart failure, and urgent heart failure visit in adults with heart failure or type 2 diabetes, chronic kidney disease, and other cardiovascular risk factors ...
It is indicated in adults for the treatment of symptomatic chronic heart failure; [13] and it is indicated in adults for the treatment of chronic kidney disease. [13] Empagliflozin lowers risk of hospitalization and death in people with reduced heart function, when added to standard heart failure treatment with or without type 2 diabetes.
Diabetic cardiomyopathy is a disorder of the heart muscle in people with diabetes.It can lead to inability of the heart to circulate blood through the body effectively, a state known as heart failure(HF), [2] with accumulation of fluid in the lungs (pulmonary edema) or legs (peripheral edema).
The drugs used to treat heart failure in people with diabetes are often the same drugs prescribed for those without diabetes, but there’s evidence that they work even better in people with both ...
"We have been prescribing many long-term drugs for hypertension, heart disease, high cholesterol, diabetes, arthritis, reflux and many other diseases without hesitation," he said.
Dapagliflozin is used along with diet, exercise, and usually with other glucose-lowering medications, to improve glycaemic control in adults with type 2 diabetes. . Dapagliflozin, in addition to other SGLT2-inhibitors, was shown to reduce the rate of decline in kidney function and kidney failure in non-diabetic and type 2 diabetic adults when added to the existing treatment
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