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Proton-pump inhibitors have largely superseded the H 2-receptor antagonists, a group of medications with similar effects but a different mode of action, and heavy use of antacids. [3] A potassium-competitive acid blocker (PCAB) revaprazan was marketed in Korea as an alternative to a PPI.
Omeprazole is a proton-pump inhibitor (PPI) and its effectiveness is similar to that of other PPIs. [9] It can be taken by mouth or by injection into a vein . [ 1 ] [ 10 ] It is also available in the fixed-dose combination medication omeprazole/sodium bicarbonate as Zegerid [ 11 ] [ 12 ] and as Konvomep.
Lansoprazole, sold under the brand name Prevacid among others, is a medication which reduces stomach acid. [4] It is a proton pump inhibitor (PPI), used to treat peptic ulcer disease, gastroesophageal reflux disease, and Zollinger–Ellison syndrome. [5] Its effectiveness is similar to that of other PPIs. [6] It is taken by mouth. [4]
[5] [6] It may also be used along with other medications to eliminate Helicobacter pylori. [7] Pantoprazole is a proton-pump inhibitor (PPI) and its effectiveness is similar to that of other PPIs. [8] It is available by mouth and by injection into a vein. [5] Common side effects include headaches, diarrhea, abdominal pain, and joint pain.
A derivative of timoprazole, omeprazole, was discovered in 1979, and was the first of a new class of drug that control acid secretion in the stomach, a proton pump inhibitor (PPI). [ 11 ] [ 12 ] Addition of 5-methoxy-substitution to the benzimidazole moiety of omeprazole was also made and gave the compound much more stability at neutral pH. [ 6 ]
Pages in category "Proton-pump inhibitors" The following 18 pages are in this category, out of 18 total. This list may not reflect recent changes. A. Azeloprazole; D.
Ilaprazole (trade name Noltec) is a proton pump inhibitor (PPI) used in the treatment of dyspepsia, peptic ulcer disease (PUD), gastroesophageal reflux disease (GORD/GERD) [1] and duodenal ulcer. [2] [3] It is available in strengths of 5, 10, and 20 mg.
With the development of proton pump inhibitors, such as omeprazole, approved for the same indications, cimetidine is available as an over-the-counter formulation to prevent heartburn or acid indigestion, along with the other H2-receptor antagonists. [12] Cimetidine was developed in 1971 and came into commercial use in 1977.
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