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Urolithins are microflora metabolites of dietary ellagic acid derivatives, such as ellagitannins. [1] They are produced in the gut , and found in the urine in the form of urolithin B glucuronide after absorption of ellagitannins-containing foods, such as pomegranate . [ 2 ]
Urolithin A is not known to be found in any food but rather forms as the result of transformation of ellagic acids and ellagitannins by the gut microflora in humans. [ citation needed ] Sources of ellagitannins are: pomegranates, nuts, some berries (raspberries, strawberries, blackberries, cloudberries), tea, muscadine grapes, many tropical ...
As heart development continues, this tube undergoes remodeling to eventually form the four-chambered heart. The endocardial cushions are a subset of cells found in the developing heart tube that will give rise to the heart's primitive valves and septa , critical to the proper formation of a four-chambered heart.
In relation to the rib cage, the coronary sulcus spans from the medial side of the 3rd left costal cartilage, to the middle of the right 6th costal cartilage. [1] Epicardial fat tends to be concentrated along the coronary sulcus. [4] [5] There are two coronary sulci in the heart, including left and right coronary sulci.
The Purkinje fibers, named for Jan Evangelista Purkyně, (English: / p ɜːr ˈ k ɪ n dʒ i / pur-KIN-jee; [1] Czech: [ˈpurkɪɲɛ] ⓘ; Purkinje tissue or subendocardial branches) are located in the inner ventricular walls of the heart, [2] just beneath the endocardium in a space called the subendocardium.
Urolithin B is found in the urine in the form of urolithin B glucuronide. [citation needed] See also. Glucuronide. Glucuronic acid; Pomegranate ellagitannins;
The pericardium (pl.: pericardia), also called pericardial sac, is a double-walled sac containing the heart and the roots of the great vessels. [1] It has two layers, an outer layer made of strong inelastic connective tissue (fibrous pericardium), and an inner layer made of serous membrane (serous pericardium).
The crux cordis or crux of the heart (from Latin "crux" meaning "cross") is the area on the lower back side of the heart where the coronary sulcus (the groove separating the atria from the ventricles) and the posterior interventricular sulcus (the groove separating the left from the right ventricle) meet. [1]