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H5N1 influenza virus is a type of influenza A virus which mostly infects birds. H5N1 flu is a concern because its global spread may constitute a pandemic threat. The yardstick for human mortality from H5N1 is the case-fatality rate (CFR); the ratio of the number of confirmed human deaths resulting from infection of H5N1 to the number of those confirmed cases of infection with the virus.
In June 2006 WHO predicted an upsurge in human deaths due to H5N1 during late 2006 or early 2007 following a summer/fall lull in most countries, as H5N1 appears to be somewhat seasonal in nature. In July and August 2006 significantly increased numbers of bird deaths due to H5N1 were recorded in Cambodia , China , Laos , Nigeria , and Thailand ...
[26] [27] [28] Further sequencing determined that at least one of the two cases was from an older H5N1 clade, 2.3.2.1c, which had circulated as a common H5N1 strain in Cambodia for many years, rather than the more recent clade 2.3.4.4b, which had caused mass poultry deaths since 2020. This older clade had jumped to humans in the past yet hadn't ...
Doug Corwin, owner of Crescent Duck Farm, carries a female duck used for breeding in 2014 in Aquebogue, New York. Millions of birds have been killed in response to the spread of H5N1 bird flu.
H5N1 is a shapeshifter, so to speak, due to its segmented DNA, Michael explains. “For example, if a human gets infected with a bird flu and also carries a human influenza A virus, these two ...
Most human cases of bird flu in North America have been mild, a fact that’s underscored by a new study of the first 46 confirmed human H5N1 infections in the United States this year.
Human infectious diseases may be characterized by their case fatality rate (CFR), the proportion of people diagnosed with a disease who die from it (cf. mortality rate).It should not be confused with the infection fatality rate (IFR), the estimated proportion of people infected by a disease-causing agent, including asymptomatic and undiagnosed infections, who die from the disease.
Between 2003 and December 2024, the World Health Organization has recorded 963 cases of confirmed H5N1 influenza, leading to 465 deaths. [48] The true fatality rate may be lower because some cases with mild symptoms may not have been identified as H5N1.