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The parenteral route is any route that is not enteral (par-+ enteral). Parenteral administration can be performed by injection, that is, using a needle (usually a hypodermic needle) and a syringe, [16] or by the insertion of an indwelling catheter. Locations of application of parenteral administration include: Central nervous system:
Enteral administration is food or drug administration via the human gastrointestinal tract. This contrasts with parenteral nutrition or drug administration (Greek para, "besides" + enteros), which occurs from routes outside the GI tract, such as intravenous routes. Enteral administration involves the esophagus, stomach, and small and large ...
Systemic administration is a route of administration of medication, nutrition or other substance into the circulatory system so that the entire body is affected. [1] Administration can take place via enteral administration (absorption of the drug through the gastrointestinal tract) [ 2 ] or parenteral administration (generally injection ...
The pharmacological agents used differ depending on patient, level of sedation desired and medical professional administering the sedation medications. The medications can belong to a class of drugs called sedatives, which exert their action by depressing the central nervous system, specifically those areas concerned with conscious awareness ...
Before administration, a lyophilized drug is reconstituted as a liquid before being administered. This is done by combining a liquid diluent with the freeze-dried powder, mixing, then injecting. Reconstitution usually requires a reconstitution and delivery system to ensure that the drug is correctly mixed and administered.
Drug delivery is a concept heavily integrated with dosage form and route of administration, the latter sometimes being considered part of the definition. [9] While route of administration is often used interchangeably with drug delivery, the two are separate concepts.
Administration of individual components may be more hazardous than administration of pre-mixed solutions such as those used in total parenteral nutrition, because the latter are generally already balanced in regard to e.g. osmolarity and ability to infuse peripherally.
Sublingual and buccal drugs are not enteral because they do not enter the GI system. Parenteral is all other delivery mechanisms that do not involve the gastointestinal system. Traditionally, parenteral means "by injection", but again, because of advances in the science, parenteral now includes many other mechanisms of delivery including ...
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