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CD25 deficiency or interleukin 2 receptor alpha deficiency is an immunodeficiency disorder associated with mutations in the interleukin 2 receptor alpha (CD25) (IL2RA) gene. The mutations cause expression of a defective α chain or complete absence thereof, an essential part of high-affinity interleukin-2 (IL-2) receptors.
This is a list of lists of deaths of notable people, organized by year. New deaths articles are added to their respective month (e.g., Deaths in February 2025 ) and then linked below. 2025
Thomas A. Waldmann was born in New York City as the only child of Elisabeth Sipos and Charles Waldmann. He received his M.D. from Harvard Medical School in 1955. He joined the National Cancer Institute in 1956 and became chief of the Lymphoid Malignancies Branch (formerly Metabolism Branch) in 1973.
3559 16184 Ensembl ENSG00000134460 ENSMUSG00000026770 UniProt P01589 P01590 RefSeq (mRNA) NM_000417 NM_001308242 NM_001308243 NM_008367 RefSeq (protein) NP_000408 NP_001295171 NP_001295172 NP_032393 Location (UCSC) Chr 10: 6.01 – 6.06 Mb Chr 2: 11.65 – 11.7 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse The interleukin-2 receptor alpha chain (also called Tac antigen, P55, and ...
IL-2 binds to the IL-2 receptor, which has three forms, generated by different combinations of three different proteins, often referred to as "chains": α (alpha) (also called IL-2Rα, CD25, or Tac antigen), β (beta) (also called IL-2Rβ, or CD122), and γ (gamma) (also called IL-2Rγ, γ c, common gamma chain, or CD132); these subunits are also parts of receptors for other cytokines.
This is a list of people who died in the last 5 days with an article at the English Wikipedia. For people without an English Wikipedia page see: Wikipedia:Database reports/Recent deaths (red links). Generally updated at least daily, last time: 10:59, 14 February 2025 (UTC).
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PDL2 or PDCD1LG2 (Programmed Cell Death 1 Ligand 2); on Dendritic cells, Macrophages etc. Ligand for PD-1 (CD279) CD274: PDL1 or PDCD1L1 (Programmed Cell Death 1 Ligand 1); expressed on T cells, NK cells, macrophages, myeloid DCs, B cells, epithelial cells, and vascular endothelial cells and others. Ligand for PD1 (CD279) and also CD80 (B7-1).