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The partition coefficient of PEG 400 between hexane and water is 0.000015 (log =), indicating that when PEG 400 is mixed with water and hexane, there are only 15 parts of PEG400 in the hexane layer per 1 million parts of PEG 400 in the water layer. [1] PEG 400 is soluble in water, acetone, alcohols, benzene, glycerin, glycols, and aromatic ...
The numbers that are often included in the names of PEGs indicate their average molecular weights (e.g. a PEG with n = 9 would have an average molecular weight of approximately 400 daltons, and would be labeled PEG 400). Most PEGs include molecules with a distribution of molecular weights (i.e. they are polydisperse).
Macrogol 4000, pharmaceutical quality. Macrogol 3350, often in combination with electrolytes, is used for short-term relief of constipation as well as for long-term use in constipation of various causes, including in multiple sclerosis and Parkinson's disease patients (an often-overlooked non-motor symptom) as well as constipation caused by pharmaceutical drugs such as opioids and ...
Ethylene oxide reacts with water to produce ethylene glycol according to the chemical equation. C 2 H 4 O + H 2 O → HO−CH 2 CH 2 −OH. This reaction can be catalyzed by either acids or bases, or can occur at neutral pH under elevated temperatures. The highest yields of ethylene glycol occur at acidic or neutral pH with a large excess of water.
Solubility in water decreases rapidly with increasing molar mass. Secondary hydroxyl groups in PPG are less reactive than primary hydroxyl groups in polyethylene glycol. PPG is less toxic than PEG, so biotechnologicals are now mainly produced with PPG. [4] [5] [6] Difference in water solubility of PPG4000 and PPG400
Polyols may be classified according to their chemistry. [5] Some of these chemistries are polyether, polyester, [6] polycarbonate [7] [8] and also acrylic polyols. [9] [10] Polyether polyols may be further subdivided and classified as polyethylene oxide or polyethylene glycol (PEG), polypropylene glycol (PPG) and Polytetrahydrofuran or PTMEG.
Most of the common uses of poloxamer 407 are related to its surfactant properties. For example, it is widely used in cosmetics for dissolving oily ingredients in water.It can also be found in multi-purpose contact lens cleaning solutions, where its purpose there is to help remove lipid films from the lens.
Table obtained from Lange's Handbook of Chemistry, 10th ed. Specific gravity is referenced to water at 15.6 °C. See also "Typical Freezing and Boiling Points of Aqueous Solutions of DOWTHERM SR-1 and DOWTHERM-SR4000" (PDF). Dow Chemical. Archived from the original (PDF) on 27 September 2007
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