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Pseudobulbar affect (PBA), or emotional incontinence, is a type of neurological disorder characterized by uncontrollable episodes of crying or laughing. PBA occurs secondary to a neurologic disorder or brain injury. Patients may find themselves crying uncontrollably at something that is only slightly sad, being unable to stop themselves for ...
Avanir Pharmaceuticals (NAS: AVNR) is a biotechnology company developing therapies focused on the central nervous system. It has one drug currently approved by the Food and Drug Administration ...
Since pseudobulbar palsy is a syndrome associated with other diseases, treating the underlying disease may eventually reduce the symptoms of pseudobulbar palsy. [ citation needed ] Possible pharmacological interventions for pseudobulbar affect include the tricyclic antidepressants , serotonin reuptake inhibitors , and a novel approach utilizing ...
Download as PDF; Printable version; ... is a fixed-dose combination medication for the treatment of pseudobulbar affect ... and is marketed by Avanir Pharmaceuticals. [4]
Avanir Pharmaceuticals had high hopes for AVP-923, a neuropathy pain treatment for Alzheimer's, Parkinson's, and autism. However, AVP-923 failed to do better than placebo in a key mid-stage ...
Central pontine myelinolysis is a neurological condition involving severe damage to the myelin sheath of nerve cells in the pons (an area of the brainstem). It is predominately iatrogenic (treatment-induced), and is characterized by acute paralysis, dysphagia (difficulty swallowing), dysarthria (difficulty speaking), and other neurological symptoms.
Hi there, I think "labile affect" is referring quite specifically to the neurological manifestation which either occurs without stimuli or is much more exaggerated than one would normally expect. By contrast, tearfulness during depression or bereavement is a perfectly normal symptom and so isn't really pathological in the way that labile affect is.
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