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Midazolam is known to cause respiratory depression. In healthy humans, 0.15 mg/kg of midazolam may cause respiratory depression, which is postulated to be a central nervous system (CNS) effect. [48] When midazolam is administered in combination with fentanyl, the incidence of hypoxemia or apnea becomes more likely. [49]
Automated blood pressure measurements over 15 to 20 minutes in a quiet part of the office or clinic can reduce (but not eliminate) incorrect blood pressure measures. [8] People with white coat hypertension do not exhibit the signs indicative of trepidation and their increased blood pressure is often not accompanied by tachycardia. [9]
Blood pressure (BP) is the pressure of circulating blood against the walls of blood vessels. Most of this pressure results from the heart pumping blood through the circulatory system . When used without qualification, the term "blood pressure" refers to the pressure in a brachial artery , where it is most commonly measured.
The blood pressure reading is recorded as two numbers, systolic and diastolic. The systolic blood pressure represents the amount of pressure the blood is applying against artery walls during heartbeats whereas the diastolic blood pressure shows while the heart is resting between beats. [citation needed]
When symptoms increase periodically during protracted withdrawal, physiological changes may be present, including dilated pupils as well as an increase in blood pressure and heart rate. [9] The change in symptoms has been proposed to be due to changes in receptor sensitivity for GABA during the process of tolerance reversal. [ 25 ]
What is a normal blood pressure reading? Updated May 17, 2019 at 1:19 PM When Dr. Oz sat Rachael Ray down for a blood pressure test during a segment of her show, he wasn't entirely pleased with ...
"Time to peak" refers to when maximum levels of the drug in the blood occur after a given dose. Benzodiazepines generally share the same pharmacological properties, such as anxiolytic, sedative, hypnotic, skeletal muscle relaxant, amnesic, and anticonvulsant effects. Variation in potency of certain effects may exist amongst individual ...
Cushing reflex (also referred to as the vasopressor response, the Cushing effect, the Cushing reaction, the Cushing phenomenon, the Cushing response, or Cushing's Law) is a physiological nervous system response to increased intracranial pressure (ICP) that results in Cushing's triad of increased blood pressure, irregular breathing, and bradycardia. [1]