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Dermatology. Chemotherapy-induced acral erythema, also known as palmar-plantar erythrodysesthesia or hand-foot syndrome is reddening, swelling, numbness and desquamation (skin sloughing or peeling) on palms of the hands and soles of the feet (and, occasionally, on the knees, elbows, and elsewhere) that can occur after chemotherapy in patients ...
Rheumatic diseases affect various parts of the body, including the bones, joints, muscles, organs, skin, and eyes. Some, like rheumatoid arthritis and lupus, are autoimmune conditions in which the ...
Psoriatic arthritis (PsA) is a long-term inflammatory arthritis that occurs in people affected by the autoimmune disease psoriasis. [1][2] The classic feature of psoriatic arthritis is swelling of entire fingers and toes with a sausage-like appearance ("sausage digit"). [3]
In the absence of Graves' ophthalmopathy, patients may demonstrate other ophthalmic symptoms and signs due to hyperthyroidism: Dry eyes (due to loss of corneal moisture). [24] A sense of irritation, discomfort, or pain in the eyes. A tingling sensation behind the eyes or the feeling of grit or sand in the eyes.
Peeling skin syndrome 5 is caused by a genetic defect in the serpin (serpin family member 8) gene. This gene is produced by platelets and can bind to and inhibit the function of furin, which is a serine protease involved in platelet functions. It is also characterized by superficial peeling of the dorsal and palmar pores and skin of the hands ...
Rheumatoid arthritis (RA) is a long-term autoimmune disorder that primarily affects joints. [1] It typically results in warm, swollen, and painful joints. [1] Pain and stiffness often worsen following rest. [1] Most commonly, the wrist and hands are involved, with the same joints typically involved on both sides of the body. [1]
Chilblain lupus erythematosus is characterized by a rash that primarily affects acral surfaces that are frequently exposed to cold temperatures, such as the toes, fingers, ears, and nose. The rash is defined by oedematous skin, nodules, and tender plaques with a purple discoloration. [ 3 ]
Psoriasis is a long-lasting, noncontagious autoimmune disease characterized by patches of abnormal skin. [ 4 ][ 5 ] These areas are red, pink, or purple, dry, itchy, and scaly. [ 8 ][ 3 ] Psoriasis varies in severity from small localized patches to complete body coverage. [ 3 ] Injury to the skin can trigger psoriatic skin changes at that spot ...
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