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Follow-up: over 26 weeks: On average, people receiving risperidone scored higher than people treated with olanzapine. There was no clear difference between the groups. The meaning of this in day-to-day care is unclear. This finding is based on data of moderate quality. MD 0.97 higher (1.1 lower to 3.05 higher) Moderate
People on typical antipsychotics tend to have a higher rate of extrapyramidal side effects while some atypicals are associated with considerable weight gain, diabetes, and risk of metabolic syndrome; this is most pronounced with olanzapine, while risperidone and quetiapine are also associated with weight gain. [9]
Another method is "defined daily dose" (DDD), which is the assumed average dose of an antipsychotic that an adult would receive during long-term treatment. [15] DDD is primarily used for comparing the utilization of antipsychotics (e.g. in an insurance claim database), rather than comparing therapeutic effects between antipsychotics. [15]
It’s recommended that adults over 50 get the two-dose Shingrix vaccine, which is given between two and six months apart, Dr. Yoon says. ... meningitis and blood infections, and older people (and ...
The atypical antipsychotics (AAP), also known as second generation antipsychotics (SGAs) and serotonin–dopamine antagonists (SDAs), [1] [2] are a group of antipsychotic drugs (antipsychotic drugs in general are also known as tranquilizers and neuroleptics, although the latter is usually reserved for the typical antipsychotics) largely introduced after the 1970s and used to treat psychiatric ...
Paliperidone is the primary active metabolite of the older antipsychotic risperidone. [ 28 ] [ unreliable medical source? ] While its specific mechanism of action is unknown, it is believed paliperidone and risperidone act via similar, if not identical, pathways. [ 29 ]
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In older people with dementia, its use increases the risk of death. [11] Use in the third trimester of pregnancy may result in a movement disorder in the baby for some time after birth. [ 11 ] Quetiapine is believed to work by blocking a number of receptors, including those for serotonin and dopamine .