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Mephedrone, also known as 4-methylmethcathinone, 4-MMC, and 4-methylephedrone, is a synthetic stimulant drug belonging to the amphetamine and cathinone classes. It is commonly referred to by slang names such as drone, [5] M-CAT, [6] white magic, [7] meow meow, and bubble. [8]
3-Methylmethcathinone (3-MMC), also known as metaphedrone, [4] is a designer drug from the substituted cathinone family. 3-MMC is a monoamine transporter substrate (a substance acted upon by monoamine transporters) that potently releases and inhibits the reuptake of dopamine and norepinephrine, as well as displaying moderate serotonin releasing activity.
Methcathinone / ˌ m ɛ θ ˈ k æ θ ɪ ˌ n oʊ n / (α-methyl amino-propiophenone or ephedrone) (sometimes called "cat" or "jeff" or "catnip" or "M-Kat" or "kat" or "intash") is a monoamine alkaloid and psychoactive stimulant, a substituted cathinone.
Pharmacodynamics (PD) is the study of the biochemical and physiologic effects of drugs (especially pharmaceutical drugs). The effects can include those manifested within animals (including humans), microorganisms, or combinations of organisms (for example, infection).
Bath salts usually contain cathinones, typically methylenedioxypyrovalerone (MDPV, also known as "monkey dust", although this term can refer to MDPHP as well [8]), methylone or mephedrone; however, the chemical composition varies widely [6] [9] and products labeled with the same name may also contain derivatives of pyrovalerone or pipradrol.
Effects of 4-CMC and mephedrone on inhibition of neurotransmitter uptake [3] Drug Uptake Inhibition at DAT. IC 50 (nM) Uptake Inhibition at NET. IC 50 (nM) Uptake Inhibition at SERT. IC 50 (nM) Mephedrone 769 ± 106 319 ± 40 600 ± 99 4-CMC 1014 ± 78 559 ± 57 542 ± 38
Since the human body can’t produce essential fatty acids on its own, they must come from food or supplements. Diet is the main route of exposure for micro- and nanoplastics, Landrigan said ...
In the second body the concentration in the femoral blood sample was 9.6 μg/g, with Methedrone being the only toxic compound detected. The scientific investigation [ 3 ] of these cases suggests that the Methedrone alone was responsible for these deaths and that the concentrations in the femoral blood represent the fatal levels of methedrone.