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  2. Congenital insensitivity to pain - Wikipedia

    en.wikipedia.org/wiki/Congenital_insensitivity...

    Because children and adults with the disorder cannot feel pain, they may not respond to problems, thus being at a higher risk of more severe diseases. Children with this condition often sustain oral cavity damage both in and around the oral cavity (such as having bitten off the tip of their tongue) or fractures to bones. [2]

  3. Congenital insensitivity to pain with anhidrosis - Wikipedia

    en.wikipedia.org/wiki/Congenital_insensitivity...

    Those affected are unable to feel pain and temperature. [2] [3] The absence of pain experienced by people with CIPA puts them at high risk for accidental self-injury. Corneal ulceration occurs due to a lack of protective impulses. [4] Joint and bone problems are common due to repeated injuries, and wounds heal poorly. [5]

  4. List of chronic pain syndromes - Wikipedia

    en.wikipedia.org/wiki/List_of_chronic_pain_syndromes

    [3] [4] Chronic pain is considered a syndrome because of the associated symptoms that develop in those experiencing this disorder. [5] Chronic pain affects approximately 20% of people worldwide and accounts for 15–20% of visits to a physician. [3] Pain can be categorized according to its location, cause, or the anatomical system which it affects.

  5. Childhood chronic pain - Wikipedia

    en.wikipedia.org/wiki/Childhood_chronic_pain

    Paediatric chronic pain often impacts quality of life for the families of children affected, with mothers having particularly low health-related quality of life on average. [31] Parents of children with chronic pain conditions allocate considerable physical, financial, and emotional resources towards health care for their child.

  6. Cryoprecipitate - Wikipedia

    en.wikipedia.org/wiki/Cryoprecipitate

    Cryoprecipitate, also called cryo for short, or Cryoprecipitate Antihemophilic factor (AHF), is a frozen blood product prepared from blood plasma. [1] To create cryoprecipitate, Plasma is slowly thawed to 1–6 °C. A cold-insoluble precipitate is formed, which is collected by centrifugation, resuspended in a small amount of residual plasma ...

  7. Chronic pain - Wikipedia

    en.wikipedia.org/wiki/Chronic_pain

    The International Association for the Study of Pain (IASP) defines chronic pain as a general pain without biological value that sometimes continues even after the healing of the affected area; [8] [9] a type of pain that cannot be classified as acute pain [b] and lasts longer than expected to heal, or typically, pain that has been experienced on most days or daily for the past six months, is ...

  8. Familial episodic pain syndrome - Wikipedia

    en.wikipedia.org/.../Familial_episodic_pain_syndrome

    This type of familial episodic pain syndrome is characterized by childhood-onset intense episodic pain on the lower and sometimes upper extremities, this pain typically lasts days and can be treated with anti-inflammatory medication, the pain episodes tend to lower in severity with age. It is caused by mutations in the SCN11A gene, in chromosome 3.

  9. Batten disease - Wikipedia

    en.wikipedia.org/wiki/Batten_disease

    Over time, affected children experience mental impairment, worsening seizures and progressive loss of sight, speech and motor skills. Batten disease is a terminal disease; life expectancy varies depending on the type or variation. [7] [8] Females with juvenile Batten disease show first symptoms a year later than males, but on average die a year ...