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In contrast, paracellular transport is the transfer of substances across an epithelium by passing through an intercellular space between the cells. 1. It differs from transcellular transport, where the substances travel through the cell passing through both the apical membrane and basolateral membrane. 2. Renal physiology.
In cellular biology, active is the movement of molecules or ions across a cell membrane from a region of lower concentration to a region of higher concentration —against the concentration gradient. Active transport requires cellular energy to achieve this movement. There are two types of active transport: primary active transport that uses ...
These co-transporters are an example of secondary active transport. Members of the GLUT family of glucose uniporters then transport the glucose across the basolateral membrane, and into the peritubular capillaries. Because sodium and glucose are moved in the same direction across the membrane, SGLT1 and SGLT2 are known as symporters.
Cotransporters are capable of moving solutes either up or down gradients at rates of 1000 to 100000 molecules per second. They may act as channels or transporters, depending on conditions under which they are assayed. The movement occurs by binding to two molecules or ions at a time and using the gradient of one solute's concentration to force ...
Endocytosis. Endocytosis is a cellular process in which substances are brought into the cell. The material to be internalized is surrounded by an area of cell membrane, which then buds off inside the cell to form a vesicle containing the ingested materials. Endocytosis includes pinocytosis (cell drinking) and phagocytosis (cell eating).
This process is referred to as active transport. For instance, inhibiting vesicular H +-ATPases would result in a rise in the pH within vesicles and a drop in the pH of the cytoplasm. All of the ATPases share a common basic structure. Each rotary ATPase is composed of two major components: F 0 /A 0 /V 0 and F 1 /A 1 /V 1. They are connected by ...
Organo anion transporter family. Members of the Organo Anion Transporter (OAT) Family (organic-anion-transporting polypeptides, OATP) are membrane transport proteins or 'transporters' that mediate the transport of mainly organic anions across the cell membrane. Therefore, OATPs are present in the lipid bilayer of the cell membrane, acting as ...
Na–K–Cl cotransporter. The Na–K–Cl cotransporter (NKCC) is a transport protein that aids in the secondary active transport of sodium, potassium, and chloride into cells. [1] In humans there are two isoforms of this membrane transport protein, NKCC1 and NKCC2, encoded by two different genes (SLC12A2 and SLC12A1 respectively). Two ...