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Oral drugs are normally taken as tablets or capsules. The drug (active substance) itself needs to be soluble in aqueous solution at a controlled rate.Such factors as particle size and crystal form can significantly affect dissolution.
Clark's rule is a medical term referring to a mathematical formula used to calculate the proper dosage of medicine for children aged 2–17 based on the weight of the patient and the appropriate adult dose. [1] The formula was named after Cecil Belfield Clarke (1894–1970), a Barbadian physician who practiced throughout the UK, the West Indies ...
Pharmacy informatics is the combination of pharmacy practice science and applied information science. [31] Pharmacy informaticists work in many practice areas of pharmacy, however, they may also work in information technology departments or for healthcare information technology vendor companies. As a practice area and specialist domain ...
K is the clearance [mL/min] or [m 3 /s] C is the concentration [mmol/L] or [mol/m 3 ] (in the United States often [mg/mL]) From the above definitions it follows that d C d t {\displaystyle {\frac {dC}{dt}}} is the first derivative of concentration with respect to time, i.e. the change in concentration with time.
The history of pharmacy as a modern and independent science dates back to the first third of the 19th century. Before then, pharmacy evolved from antiquity as part of medicine . Before the advent of pharmacists, there existed apothecaries that worked alongside priests and physicians in regard to patient care.
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Pharmaceutical Development and Regulation 1 ((3)), 159–168. Werner, E., In silico multicellular systems biology and minimal genomes, DDT vol 8, no 24, pp 1121–1127, Dec 2003. (Introduces the concepts MCPD and Net-MCPD) Dr. David W. A. Bourne, OU College of Pharmacy Pharmacokinetic and Pharmacodynamic Resources.