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14-3-3 proteins are a family of conserved regulatory molecules that are expressed in all eukaryotic cells. 14-3-3 proteins have the ability to bind a multitude of functionally diverse signaling proteins, including kinases, phosphatases, and transmembrane receptors. More than 200 signaling proteins have been reported as 14-3-3 ligands.
2810 55948 Ensembl ENSG00000175793 ENSMUSG00000047281 UniProt P31947 O70456 RefSeq (mRNA) NM_006142 NM_018754 RefSeq (protein) NP_006133 NP_061224 Location (UCSC) Chr 1: 26.86 – 26.86 Mb Chr 4: 133.33 – 133.33 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Stratifin (also known as 14-3-3 protein sigma or 14-3-3σ protein) is a protein encoded by the SFN gene in humans. The ...
14-3-3ζ is one of 7 members of the 14-3-3 protein family, which is ubiquitously expressed and highly conserved among plants and mammals. [6] [7] [11] [12] This protein family is known for regulating signal transduction pathways primarily through binding phosphoserine proteins, though it can also bind phosphothreonine proteins and unphosphorylated proteins.
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7531 22627 Ensembl ENSG00000274474 ENSG00000108953 ENSMUSG00000020849 UniProt P62258 P62259 RefSeq (mRNA) NM_006761 NM_009536 RefSeq (protein) NP_006752 NP_033562 Location (UCSC) Chr 17: 1.34 – 1.4 Mb Chr 11: 75.62 – 75.66 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse 14-3-3 protein epsilon is a protein that in humans is encoded by the YWHAE gene. Function This gene product ...
14-3-3 protein gamma is a protein that in humans is encoded by the YWHAG gene. [5] [6] This gene product belongs to the 14-3-3 protein family which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 100% identical to the rat ...
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7529 54401 Ensembl ENSG00000166913 ENSMUSG00000018326 UniProt P31946 Q4VY19 Q9CQV8 RefSeq (mRNA) NM_139323 NM_003404 NM_018753 RefSeq (protein) NP_003395 NP_647539 NP_061223 Location (UCSC) Chr 20: 44.89 – 44.91 Mb Chr 2: 163.84 – 163.86 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse 14-3-3 protein beta/alpha is a protein that in humans is encoded by the YWHAB gene. Function ...