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[3] [4] It was introduced as a sedative and medication for morning sickness without having been tested on pregnant women. [5] While initially deemed to be safe in pregnancy, concerns regarding birth defects were noted in 1961, and the medication was removed from the market in Europe that year. [3] [6]
Morning sickness affects about 70–80% of all pregnant women to some extent. [4] [5] About 60% of women experience vomiting. [2] Hyperemesis gravidarum occurs in about 1.6% of pregnancies. [1] Morning sickness can negatively affect quality of life, result in decreased ability to work while pregnant, and result in health-care expenses. [3]
Thalidomide is a known human teratogen and carries an extremely high risk of severe, life-threatening birth defects if administered or taken during pregnancy. [6] It causes skeletal deformities such as amelia (absence of legs and/or arms), absence of bones, and phocomelia (malformation of the limbs).
Scientists are moving forward with researching cures for morning sickness, including testing drugs that block GDF15 from binding to its receptor in the brain, and exposing women to the hormone ...
A woman with lower levels in her blood outside of pregnancy may be at a higher risk of developing severe morning sickness in pregnancy, known as HG, researchers said. HG can lead to prolonged ...
GDF15—a hormone that exists throughout the body in low levels, but is produced in the placenta at higher levels during pregnancy—is indeed the cause of morning sickness, a new study out of the ...
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