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  2. Addiction-related structural neuroplasticity - Wikipedia

    en.wikipedia.org/wiki/Addiction-related...

    Neuroscientists believe that drug addicts’ behavior is a direct correlation to some physiological change in their brain, caused by using drugs. This view believes there is a bodily function in the brain causing the addiction. This is brought on by a change in the brain caused by brain damage or adaptation from chronic drug use. [1] [2]

  3. Opioid overdose - Wikipedia

    en.wikipedia.org/wiki/Opioid_overdose

    Because of their effect on the part of the brain that regulates breathing, opioids can cause very slow or stopped breathing, during overdoses, leading to hypoxia [16] or death if left untreated. [1] Hypoxia is typically caused by respiratory depression. [17] [18] The brain uses oxygen to regulate the homeostasis of the body.

  4. Opioid use disorder - Wikipedia

    en.wikipedia.org/wiki/Opioid_use_disorder

    Chronic intake of opioids such as heroin may cause long-term effects in the orbitofrontal area (OFC), which is essential for regulating reward-related behaviors, emotional responses, and anxiety. [74] Moreover, neuroimaging and neuropsychological studies demonstrate dysregulation of circuits associated with emotion, stress and high impulsivity ...

  5. Heroin - Wikipedia

    en.wikipedia.org/wiki/Heroin

    A 2010 study ranking various illegal and legal drugs based on statements by drug-harm experts. Heroin was found to be the second overall most dangerous drug. [58] Heroin is classified as a hard drug in terms of drug harmfulness. Like most opioids, unadulterated heroin may lead to adverse effects. The purity of street heroin varies greatly ...

  6. Physical dependence - Wikipedia

    en.wikipedia.org/wiki/Physical_dependence

    addictive drug – psychoactive substances that with repeated use are associated with significantly higher rates of substance use disorders, due in large part to the drug's effect on brain reward systems; dependence – an adaptive state associated with a withdrawal syndrome upon cessation of repeated exposure to a stimulus (e.g., drug intake)

  7. 5 horrifying heroin effects you didn't know about - AOL

    www.aol.com/article/2016/03/23/5-horrifying...

    It's no secret that heroin, of the opioid drug family, is a dangerous epidemic in the United States. The number of U.S. deaths from heroin per year has spiked from roughly 3,000 in 2008 to roughly ...

  8. Dying To Be Free - The Huffington Post

    projects.huffingtonpost.com/projects/dying-to-be...

    Chemistry, not moral failing, accounts for the brain’s unwinding. In the laboratories that study drug addiction, researchers have found that the brain becomes conditioned by the repeated dopamine rush caused by heroin. “The brain is not designed to handle it,” said Dr. Ruben Baler, a scientist with the National Institute on Drug Abuse.

  9. Substance dependence - Wikipedia

    en.wikipedia.org/wiki/Substance_dependence

    Substance dependence, also known as drug dependence, is a biopsychological situation whereby an individual's functionality is dependent on the necessitated re-consumption of a psychoactive substance because of an adaptive state that has developed within the individual from psychoactive substance consumption that results in the experience of withdrawal and that necessitates the re-consumption ...