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Arterial stiffness occurs as a consequence of biological aging, arteriosclerosis and genetic disorders, such as Marfan, Williams, and Ehlers-Danlos syndromes. [1] Inflammation plays a major role in arteriosclerosis and arterial stiffness. [ 2 ]
Atherosclerosis [a] is a pattern of the disease arteriosclerosis, [8] characterized by development of abnormalities called lesions in walls of arteries.This is a chronic inflammatory disease involving many different cell types and is driven by elevated levels of cholesterol in the blood. [9]
Many people with early coronary artery disease don’t have any symptoms. If your heart doesn’t get enough oxygen, you might develop chest pain (angina). ... This stiffness makes it difficult ...
High blood pressure usually does not cause symptoms itself. [1] It is, however, a major risk factor for stroke, coronary artery disease, heart failure, atrial fibrillation, peripheral arterial disease, vision loss, chronic kidney disease, and dementia. [2] [3] [4] [12] Hypertension is a major cause of premature death worldwide. [13]
Dr. Jeremy London is a heart surgeon and a heart attack survivor. He operates on diseased hearts, but like many people, he ignored his own symptoms of a coronary artery blockage until it became an ...
The arterial compliance - the amount of tension produced per stretch of arteries, decreases with age, and the stiffness of arteries increases with age. [3] The structural change in blood vessels causes the elderly to be more susceptible to hypertension, which leads to complications in arteries, the heart and even the brain. [citation needed]
This then causes heart muscle and coronary artery dysfunction, resulting in severe heart failure and coronary artery disease. ... including experiencing cardiac symptoms that were resistant to ...
In hypertensive patients, a high pulse pressure can often be an indicator of conduit artery stiffness (stiffness of the major arteries). [13] When the arterial walls are stiffer (less compliant), the heart has to beat harder to overcome the resistance from the stiff arteries, resulting in an increased pulse pressure. [14]
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