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Randomization is a statistical process in which a random mechanism is employed to select a sample from a population or assign subjects to different groups. [1] [2] [3] The process is crucial in ensuring the random allocation of experimental units or treatment protocols, thereby minimizing selection bias and enhancing the statistical validity. [4]
In the statistical theory of design of experiments, randomization involves randomly allocating the experimental units across the treatment groups.For example, if an experiment compares a new drug against a standard drug, then the patients should be allocated to either the new drug or to the standard drug control using randomization.
Random assignment or random placement is an experimental technique for assigning human participants or animal subjects to different groups in an experiment (e.g., a treatment group versus a control group) using randomization, such as by a chance procedure (e.g., flipping a coin) or a random number generator. [1]
Graphic breakdown of stratified random sampling. In statistics, stratified randomization is a method of sampling which first stratifies the whole study population into subgroups with same attributes or characteristics, known as strata, then followed by simple random sampling from the stratified groups, where each element within the same subgroup are selected unbiasedly during any stage of the ...
Randomization Random assignment is the process of assigning individuals at random to groups or to different groups in an experiment, so that each individual of the population has the same chance of becoming a participant in the study.
In practice, the randomization is typically performed by a computer program. However, the randomization can also be generated from random number tables or by some physical mechanism (e.g., drawing the slips of paper).
In some cases, data reveals an obvious non-random pattern, as with so-called "runs in the data" (such as expecting random 0–9 but finding "4 3 2 1 0 4 3 2 1..." and rarely going above 4). If a selected set of data fails the tests, then parameters can be changed or other randomized data can be used which does pass the tests for randomness.
To address nuisance variables, researchers can employ different methods such as blocking or randomization. Blocking involves grouping experimental units based on levels of the nuisance variable to control for its influence. Randomization helps distribute the effects of nuisance variables evenly across treatment groups.