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The mainstay of treatment for schizophrenia is an antipsychotic medication. [5] Most antipsychotics can take around 7 to 14 days to have their full effect. Medication may improve the positive symptoms of schizophrenia, and social and vocational functioning. [6]
Positive symptoms are those symptoms that are not normally experienced, but are present in people during a psychotic episode in schizophrenia, including delusions, hallucinations, and disorganized thoughts, speech and behavior or inappropriate affect, typically regarded as manifestations of psychosis. [36]
Metacognitive training (MCT) is an approach for treating the symptoms of psychosis in schizophrenia, [1] especially delusions, [2] which has been adapted for other disorders such as depression, obsessive–compulsive disorder and borderline over the years (see below). It was developed by Steffen Moritz and Todd Woodward.
The first-line psychiatric treatment for schizophrenia is antipsychotic medication, [11] which can reduce the positive symptoms of schizophrenia in about 8–15 days. . Antipsychotics only appear to improve secondary negative symptoms of schizophrenia in the short term and may worsen negative symptoms over
Higher doses (greater than 400 mg) act upon post-synaptic dopamine receptors resulting in a reduction in the positive symptoms of schizophrenia, such as psychosis. Lower doses, however, act upon dopamine autoreceptors, resulting in increased dopamine transmission, improving the negative symptoms of schizophrenia.
It treats both the positive and negative symptoms of schizophrenia. [13] Asenapine binds D 2, D 3 and D 4 [18] and is used to treat bipolar disorder and schizophrenia. [19] Its side effects include weight gain but there is lower risk for orthostatic hypotension and hyperprolactinemia. Aripiprazole binds D 2 as a partial agonist but antagonizes ...
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