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Here’s how they affected whether or not patients would achieve 10% or greater weight loss: Active agent: Patients who took semaglutide were more than twice as likely compared to those taking ...
One important note — semaglutide is considered a safe drug, and for many, the benefits outweigh any potential long-term risks. A healthcare professional can help make sure semaglutide is safe ...
Given that people on other prescription weight-loss medications lose, on average, 3% to 12% of their body weight after a year, it’s not surprising that semaglutide’s results are leading some ...
While, they don’t fully understand why, it’s possible, Al-Aly says, that when patients lose weight on the GLP-1s, their blood pressure improves—but their anti-hypertensive medications are ...
In March 2023, a Novo Nordisk official said, based on a randomized, double-blind study (NCT03548935 [107]) funded by the company, that patients using semaglutide to lose weight regained two-thirds of their original weight loss one year (52 weeks) after discontinuing use of the drug. After two years (120 weeks), the patients retained roughly one ...
Preliminary trial results found a greater weight loss compared to either medication alone. HbA1c was significantly improved compared to cagrilintide alone and non-significantly better than semaglutide alone. [1] [2] In a Phase II trial, weight loss averaged -15.6 percent after 32 weeks, making CagriSema comparable in efficacy to tirzepatide.
In clinical trials of Wegovy, which included a higher dose of injectable semaglutide (2.4 mg), people lost an average of almost 15 percent of their body weight.
In the early 2020s, GLP-1 receptor agonists such as semaglutide or tirzepatide became popular for weight loss because they are more effective than earlier drugs, causing a shortage for patients prescribed these medications for type 2 diabetes, their original indication. [41] [42]
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