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Leptospirosis is a blood infection caused by the bacterium Leptospira [8] that can infect humans, dogs, rodents and many other wild and domesticated animals. [8] Signs and symptoms can range from none to mild (headaches, muscle pains, and fevers) to severe (bleeding in the lungs or meningitis). [5]
Leptospirosis in canines can be divided into the four categories of reproductive, icteric, hemorrhagic, and uremic. Reproductive leptospirosis results in the premature birth of offspring or abortion, and uremic leptospirosis is referred to as Stuttgart disease. [32] L. interrogans triggers a highly inflammatory response in infected dogs.
Leptospira noguchii is another pathogenic bacteria that causes Leptospirosis. Leptospirosis can be transferred in a multitude of ways. Leptospirosis can transfer from animals to humans , humans to humans, or animals to animals via intake of contaminated body fluids, such as urine and blood. [7]
The minimal growth temperature of pathogenic species is 13–15 °C. Because the minimal growth temperature of the saprophytes is 5–10 °C, the ability of Leptospira to grow at 13 °C can be used to distinguish saprophytic from pathogenic Leptospira species. [30] The optimal pH for growth of Leptospira is 7.2–7.6.
Conjunctival suffusion is an eye finding occurring early in leptospirosis, which is caused by Leptospira interrogans. Conjunctival suffusion is characterized by redness of the conjunctiva that resembles conjunctivitis , but it does not involve inflammatory exudates. [ 1 ]
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With P-22 as the poster cat for the project, the #savelacougars campaign helped raise the roughly $90 million needed to build what will become the world's largest wildlife bridge.
The Leptospiral culture collection consists of over 300 different types of Leptospira cultures and is one of only several collections of its kind in the world. [1] The work of the laboratory supports the fight against the disease by providing analysis and diagnostic support to public and private pathology providers, both nationally and internationally.