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Tenosynovial giant cell tumor (TGCT) is a non-malignant tumor defined histologically as inclusions of “osteoclast-like” multinucleated giant cells, hemosiderin, and macrophages. [1] This histology can present one of 2 clinically distinct ways. TGCT tumors often develop from the lining of joints (also known as synovial tissue).
Giant cell sarcoma of bone; M9251/1 Giant cell tumor of soft parts, NOS M9251/3 Malignant giant cell tumor of soft parts M9252/0 Tenosynovial giant cell tumor Fibrous histiocytoma of tendon sheath; Giant cell tumor of tendon sheath; M9252/3 Malignant tenosynovial giant cell tumor Giant cell tumor of tendon sheath, malignant
A number of tumors have giant cells, but are not true benign giant-cell tumors. These include aneurysmal bone cyst, chondroblastoma, simple bone cyst, osteoid osteoma, osteoblastoma, osteosarcoma, giant-cell reparative granuloma, Giant-cell tumor of the tendon sheath and brown tumor of hyperparathyroidism. [citation needed]
Fibroma of tendon sheath is a benign tumor that presents as a small subcutaneous nodule that slowly increases in size. [1] This is a notably uncommon condition. According to case report literature, the tumors often have a multinodular growth pattern, with individual nodules being composed of bland, slender, spindle-shaped cells (myofibroblasts) in a dense, fibrous matrix.” [2] A common ...
Benign synovioma, or giant-cell tumor of the tendon sheath; Malignant synovioma, also known as: synovial sarcoma This page was last edited on 30 ...
Ganglion cysts are not limited to the hands and feet. They may occur near the knee, commonly near the cruciate ligaments, but they may occur at the origins of the gastrocnemius tendon, and anteriorly on Hoffa's infrapatellar fat pad. [14] At the shoulder, they typically occur at the acromioclavicular joint or along the biceps tendon. [15]
The name "synovial sarcoma" was coined early in the 20th century, as some researchers thought that the microscopic similarity of some tumors to synovium, and its propensity to arise adjacent to joints, indicated a synovial origin; however, the actual cells from which the tumor develops are unknown and not necessarily synovial. [3]
Later on, it was common to use both neurothekeoma and nerve sheath myxoma interchangeably. [12] [13] In 2011, Sheth et al. used microarray analysis to distinguish between neurothekeoma and nerve sheath myxoma based on the genetic expression of the cells. [14] Nerve sheath myxoma is more frequent among young people without gender preference.