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It is a type of organelle made up of two subunits – rough endoplasmic reticulum (RER), and smooth endoplasmic reticulum (SER). The endoplasmic reticulum is found in most eukaryotic cells and forms an interconnected network of flattened, membrane-enclosed sacs known as cisternae (in the RER), and tubular structures in the SER.
O-GlcNAcylation and phosphorylation can occur on the same threonine and serine residues, suggesting a complex relationship between these modifications that can affect many functions of the cell. [ 6 ] [ 12 ] The modification affects processes like the cells response to cellular stress, the cell cycle, protein stability and protein turnover.
NCERT has a comprehensive extension program in which departments of the National Institute of Education, Regional Institute of Education, Central Institute of Vocational Education, and field coaches' offices in the states are engaged in activities. Several programs are organized in rural and backward areas to reach out to functionaries in these ...
The study found significant differences between human liver microsomes and human liver S9 fractions in drug-metabolizing enzyme and transporter protein concentrations. The protein-protein correlations of these drug-metabolizing enzymes and transporters was determined relating to the two hepatic preparations.
When looking at the differences between ERα and ERβ, Activating Function 1 (AF-1) and AF-2 are important. Together they play an important part in the interaction with other co-regulatory proteins that control gene transcription. [21] [4] AF-1 is located in the amino terminus of the ER and is only 20% homologous in ERα and ERβ.
On 23 February 2022, a public interest litigation petition was filed the Madras High Court seeking a direction to the State government to adopt the National Council of Educational Research and Training (NCERT) syllabus for State Board schools. The petitioners claimed that Samacheer Kalvi was not helping the students crack the competitive exams.
The South Eastern and Chatham Railway Companies Joint Management Committee (SE&CRCJMC), [2] known as the South Eastern and Chatham Railway (SE&CR), was a working union of two neighbouring rival railways, the South Eastern Railway (SER) and London, Chatham and Dover Railway (LC&DR), which operated between London and south-east England.
Réseau Express Régional, or RER d'Île-de-France, the commuter rail service serving Paris and its suburbs; Réseau Express Régional Franco-Valdo-Genevois, now called Léman Express, commuter rail service serving Geneva (Switzerland), Annemasse (France) and its suburbs