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The demyelination and scarring of axons in the neurons of the nervous system can affect their conduction properties and seriously harm the normal communication of the brain with the rest of the body. Multiple sclerosis (MS) is a disease that causes this deterioration of the myelin sheath. There isn't a unique test to diagnose MS and several ...
Electromyoneurography is a technique that uses surface electrical probes to obtain electrophysiological readings from nerve and muscle cells. The nerve activity is generally recorded using surface electrodes, stimulating the nerve at one site and recording from another with a minimum distance between the two.
Intraoperative neurophysiological monitoring (IONM) or intraoperative neuromonitoring is the use of electrophysiological methods such as electroencephalography (EEG), electromyography (EMG), and evoked potentials to monitor the functional integrity of certain neural structures (e.g., nerves, spinal cord and parts of the brain) during
Unusual types of MS have been described; these include Devic's disease, Balo concentric sclerosis, Schilder's diffuse sclerosis, and Marburg multiple sclerosis. There is debate on whether they are MS variants or different diseases. [31] Multiple sclerosis behaves differently in children, taking more time to reach the progressive stage. [5]
Tumefactive multiple sclerosis is a condition in which the central nervous system of a person has multiple demyelinating lesions with atypical characteristics for those of standard multiple sclerosis (MS). It is called tumefactive as the lesions are "tumor-like" and they mimic tumors clinically, radiologically and sometimes pathologically.
Childhood dementia is very often diagnosed late, misdiagnosed, or not diagnosed at all. [9] A correct diagnosis happens, on average, 2 years or more after symptoms become apparent. Additionally, children affected by childhood dementia are often misdiagnosed with: Autism [16] [9] [17] Developmental or intellectual delay [16] [9] ADHD [9] Others [9]
Needle EMG has limitations, however, in that it does involve voluntary activation of muscle, and as such is less informative in patients unwilling or unable to cooperate, children and infants, and in individuals with paralysis. Surface EMG can have limited applications due to inherent problems associated with surface EMG.
In fact, it seems that MS patients with anti-MOG positivity could be considered a different disease in the near future. Comparative Effectiveness Research (CER) is an emerging field in Multiple Sclerosis treatment. The response of the disease to the different available medications at this moment cannot be predicted, and would be desirable. [17]
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