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  2. Is There a "Best Time" to Take Metformin? - AOL

    www.aol.com/best-time-metformin-115700262.html

    Make it a habit to take your metformin medicine at the same time each day. Do take your medication with food. Doing so can help limit stomach or bowel problems, which are common within the first ...

  3. 6 Benefits of Taking Metformin (Besides Weight Loss) - AOL

    www.aol.com/lifestyle/6-benefits-taking...

    2. Alleviates Hunger. Metformin improves how well your cells respond to insulin. This helps regulate your blood sugar levels and manage spikes in insulin that can trigger hunger and food cravings.

  4. Top aging expert says these 4 FDA-approved drugs hold promise ...

    www.aol.com/finance/global-aging-doctor-says-4...

    One analysis found people using bisphosphonates were 15% less likely to die than nonusers after a 2.8 year follow up. Metformin Metformin, which has been around for 60 years, is the most ...

  5. Metformin - Wikipedia

    en.wikipedia.org/wiki/Metformin

    [9] [131] Peak plasma concentrations (C max) are reached within 1–3 hours of taking immediate-release metformin and 4–8 hours with extended-release formulations. [ 9 ] [ 131 ] The plasma protein binding of metformin is negligible, as reflected by its very high apparent volume of distribution (300–1000 L after a single dose).

  6. Type 1 diabetes - Wikipedia

    en.wikipedia.org/wiki/Type_1_diabetes

    People with type 1 diabetes also have increased risk of cardiovascular disease, which is estimated to shorten the life of the average type 1 diabetic by 8–13 years. [99] Cardiovascular disease [100] as well as neuropathy [101] may have an autoimmune basis, as well. Women with type 1 DM have a 40% higher risk of death as compared to men with ...

  7. Type 2 diabetes - Wikipedia

    en.wikipedia.org/wiki/Type_2_diabetes

    Lack of sleep has also been linked to type 2 diabetes. [38] Laboratory studies have linked short-term sleep deprivations to changes in glucose metabolism, nervous system activity, or hormonal factors that may lead to diabetes. [38] Dietary factors also influence the risk of developing type 2 diabetes.

  8. Here’s How to Know If Your Metformin Is Working or Not - AOL

    www.aol.com/know-metformin-working-not-164200860...

    Metformin is a tool to support lifestyle changes for conditions including type 2 diabetes and PCOS and is best used in conjunction with regular exercise, following a balanced diet, good sleep ...

  9. Advanced glycation end-product - Wikipedia

    en.wikipedia.org/wiki/Advanced_glycation_end-product

    [7] [8] [9] They are also believed to play a causative role in the vascular complications of diabetes mellitus. [10] AGEs arise under certain pathologic conditions, such as oxidative stress due to hyperglycemia in patients with diabetes. [11] AGEs play a role as proinflammatory mediators in gestational diabetes as well. [12]

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