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Hemodynamics explains the physical laws that govern the flow of blood in the blood vessels. Blood flow ensures the transportation of nutrients , hormones , metabolic waste products, oxygen , and carbon dioxide throughout the body to maintain cell-level metabolism , the regulation of the pH , osmotic pressure and temperature of the whole body ...
A lumped parameter cardiovascular model is a zero-dimensional mathematical model used to describe the hemodynamics of the cardiovascular system. Given a set of parameters that have a physical meaning (e.g. resistances to blood flow), it allows to study the changes in blood pressures or flow rates throughout the cardiovascular system.
Cardiovascular physiology is the study of the cardiovascular system, specifically addressing the physiology of the heart ("cardio") and blood vessels ("vascular").. These subjects are sometimes addressed separately, under the names cardiac physiology and circulatory physiology.
Several physiologically relevant hemodynamic parameters such as stroke volume, cardiac output, ejection fraction, myocardial contractility, etc. can be determined from these loops. To generate a PV loop for the left ventricle, the LV pressure is plotted against LV volume at multiple time points during a single cardiac cycle .
The E/A ratio is a marker of the function of the left ventricle of the heart. It represents the ratio of peak velocity blood flow from left ventricular relaxation in early diastole (the E wave) to peak velocity flow in late diastole caused by atrial contraction (the A wave). [1]
Hemodynamics is the study of blood flow in the circulatory system. Blood flow in straight sections of the arterial tree are typically laminar (high, directed wall stress), but branches and curvatures in the system cause turbulent flow. [ 2 ]
Coronary Vasculature. Coronary perfusion pressure (CPP) refers to the pressure gradient that drives coronary blood pressure.The heart's function is to perfuse blood to the body; however, the heart's own myocardium (heart muscle) must, itself, be supplied for its own muscle function.
A Wiggers diagram modified from [1]. A Wiggers diagram, named after its developer, Carl Wiggers, is a unique diagram that has been used in teaching cardiac physiology for more than a century.