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Ibuprofen, an analgesic and non-steroidal anti-inflammatory drug (NSAID), [1] is sold under many brand-names around the world. The most common are Brufen (its earliest registered trademark), Advil, Motrin, and Nurofen .
[1] [2] The compound is prepared by the reaction of sodium ibuprofenate with copper(II) sulfate. It has been suggested that copper complexes of anti-inflammatory drugs are more active than the parent drug [3] and produce fewer gastrointestinal side-effects. [4] In 2008, a United States patent was issued for the utilization of ibuprofenate ...
An equianalgesic chart is a conversion chart that lists equivalent doses of analgesics (drugs used to relieve pain). Equianalgesic charts are used for calculation of an equivalent dose (a dose which would offer an equal amount of analgesia) between different analgesics. [1]
Example of some 200 mg ibuprofen tablets A 150 ml bottle (100 mg/5 ml dosage) of ibuprofen, sold in Greece. Ibuprofen is used primarily to treat fever (including postvaccination fever), mild to moderate pain (including pain relief after surgery), painful menstruation, osteoarthritis, dental pain, headaches, and pain from kidney stones.
Copper(II) sulfate is an inorganic compound with the chemical formula Cu SO 4.It forms hydrates CuSO 4 ·nH 2 O, where n can range from 1 to 7. The pentahydrate (n = 5), a bright blue crystal, is the most commonly encountered hydrate of copper(II) sulfate, [10] while its anhydrous form is white. [11]
Nurofen is a brand of range of pain-relief medication containing ibuprofen made by the English-Dutch company Reckitt Benckiser. [1] Introduced in 1983, the Nurofen brand was acquired following Reckitt Benckiser's acquisition of Boots healthcare international in 2005 for £1.93 billion, which included Nurofen, Strepsils, and Clearasil. [2]
Ibuprofen/paracetamol, sold under the brand name Combogesic among others, is a fixed-dose combination of two medications, ibuprofen, a non-steroidal anti-inflammatory drug (NSAID); and paracetamol (acetaminophen), an analgesic and antipyretic. [6] It is available as a generic medication. [9] [10] [11]
Copper(I) sulfate, also known as cuprous sulfate, is an inorganic compound with the chemical formula Cu 2 SO 4. It is a white solid, in contrast to copper(II) sulfate, which is blue in hydrous form. Compared to the commonly available reagent, copper(II) sulfate, copper(I) sulfate is unstable and not readily available. [1]
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