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Uric acid is a heterocyclic compound of carbon, nitrogen, oxygen, and hydrogen with the formula C 5 H 4 N 4 O 3. It forms ions and salts known as urates and acid urates, such as ammonium acid urate. Uric acid is a product of the metabolic breakdown of purine nucleotides, and it is a normal component of urine. [1]
Here, a dietitian explains the best anti-inflammatory foods to eat. Foods that reduce inflammation include fatty fish, tea, walnuts, and more. Here, a dietitian explains the best anti-inflammatory ...
[20] [64] Probenecid may be used if undersecretion of uric acid is present (24-hour urine uric acid less than 800 mg). [75] It is, however, not recommended if a person has a history of kidney stones. [75] Probenecid can be used in a combined therapy with allopurinol is more effective than allopurinol monotherapy. [76] [77] [78]
Unless high blood levels of uric acid are determined in a clinical laboratory, hyperuricemia may not cause noticeable symptoms in most people. [5] Development of gout – which is a painful, short-term disorder – is the most common consequence of hyperuricemia, which causes deposition of uric acid crystals usually in joints of the extremities, but may also induce formation of kidney stones ...
Blood and urine tests that look for uric acid levels, which can be a sign of gout Blood tests for specific markers of autoimmune diseases to verify lupus or rheumatoid arthritis symptoms
Uric acid has the highest concentration of any blood antioxidant [58] and provides over half of the total antioxidant capacity of human serum. [64] Uric acid's antioxidant activities are also complex, given that it does not react with some oxidants, such as superoxide, but does act against peroxynitrite, [65] peroxides, and hypochlorous acid. [66]
Acid reflux, also known as gastroesophageal reflux disease, is a common condition that causes acid to splash from the stomach into the esophagus. The result: telltale symptoms of chest pain ...
A xanthine oxidase inhibitor is any substance that inhibits the activity of xanthine oxidase, an enzyme involved in purine metabolism.In humans, inhibition of xanthine oxidase reduces the production of uric acid, and several medications that inhibit xanthine oxidase are indicated for treatment of hyperuricemia and related medical conditions including gout. [1]
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