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Azficel-T, sold under the brand name Laviv, is a cell therapy product for the improvement of the appearance of moderate to severe nasolabial fold wrinkles in adults. [1] [2] [3] It consists of fibroblasts harvested from the patient's own skin. [2] It was approved for medical use in the United States in June 2011. [2]
Minor paralysis; function is less than clearly normal, such as flattened nasolabial fold or minor asymmetry in smile 2 Partial paralysis; particularly paralysis in lower face 3 Complete facial Hemiparesis, total paralysis in upper and lower portions of one face side
If MSC treatment becomes available for stroke patients, it is possible that current mortality and morbidity rates could substantially improve due to the direct enhancement of neuroprotection and neurorestoration mechanisms rather than only indirect facilitation or prevention of further damage, e.g. decompressive surgery.
The nasolabial folds, commonly known as "smile lines" [1] or "laugh lines", [2] [self-published source] are facial features. They are the two skin folds that run from each side of the nose to the corners of the mouth. They are defined by facial structures that support the buccal fat pad. [3] They separate the cheeks from the upper lip.
Cerebral infarction, also known as an ischemic stroke, is the pathologic process that results in an area of necrotic tissue in the brain (cerebral infarct). [1] In mid to high income countries, a stroke is the main reason for disability among people and the 2nd cause of death. [2]
The structure of desmoteplase is similar to rt-PA (), but it does not contain the plasmin-sensitive cleavage site and the lysine-binding Kringle 2 domain.As a result, desmoteplase, in comparison to rt-PA, has high fibrin selectivity (100,000- v. 550-fold increase in catalytic activity), an absence of neurotoxicity, and no apparent negative effect on the blood–brain barrier.
Watershed stroke symptoms are due to the reduced blood flow to all parts of the body, specifically the brain, thus leading to brain damage. Initial symptoms, as promoted by the American Stroke Association, are FAST, representing F = Facial weakness (droop), A = Arm weakness (drift), S = Speech difficulty (slur), and T = Time to act (priority of intervention).
A mobile stroke unit (MSU) is an ambulance that furnishes services to diagnose, evaluate, and/or treat symptoms of an acute stroke. [1] It may contain, in addition to the normal ambulance equipment, a device for brain imaging ( computerized tomography ), a point-of-care laboratory and telemedical interaction between ambulance and hospital ...
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