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The strain of Yersinia pestis responsible for the Black Death, the devastating pandemic of bubonic plague, does not appear to be a direct descendant of the Justinian plague strain. However, the spread of Justinian plague may have caused the evolutionary radiation that gave rise to the currently extant 0ANT.1 clade of strains. [44] [45]
The first plague vaccine was developed by bacteriologist Waldemar Haffkine in 1897. [3] [4] He tested the vaccine on himself to prove that the vaccine was safe.[4] [5] Later, Haffkine conducted a massive inoculation program in British India, and it is estimated that 26 million doses of Haffkine's anti-plague vaccine were sent out from Bombay between 1897 and 1925, reducing the plague mortality ...
Bubonic plague is one of three types of plague caused by the bacterium Yersinia pestis. [1] One to seven days after exposure to the bacteria, flu-like symptoms develop. [1] These symptoms include fever, headaches, and vomiting, [1] as well as swollen and painful lymph nodes occurring in the area closest to where the bacteria entered the skin. [2]
The symptoms of bubonic plague are first attested in a fragment of Rufus of Ephesus preserved by Oribasius; these ancient medical authorities suggest bubonic plague had appeared in the Roman Empire before the reign of Trajan, six centuries before arriving at Pelusium in the reign of Justinian I. [41]
The Plague of Justinian in AD 541–542 is the first known attack on record, and marks the first firmly recorded pattern of bubonic plague. This disease is thought to have originated in China. [ 19 ] It then spread to Africa from where the huge city of Constantinople imported massive amounts of grain, mostly from Egypt, to feed its citizens.
The bubonic plague still exists, but because it's treatable with antibiotics and its spread can be limited by rodent and flea control, it has become a rare condition — fewer than 20 cases ...
This is an accepted version of this page This is the latest accepted revision, reviewed on 17 December 2024. Disease caused by Yersinia pestis bacterium This article is about the disease caused by Yersinia pestis. For other uses, see Plague. Medical condition Plague Yersinia pestis seen at 200× magnification with a fluorescent label. Specialty Infectious disease Symptoms Fever, weakness ...
However, a strain of bubonic plague with high-level resistance to streptomycin has been seen in Madagascar. More than 80% of US cases have been the bubonic form, which is the most common form of ...
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