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Ions often move through the segments of the channel pore in a single file nearly as quickly as the ions move through the free solution. In many ion channels, passage through the pore is governed by a "gate", which may be opened or closed in response to chemical or electrical signals, temperature, or mechanical force. [citation needed]
Potassium ion channels play a key role in maintaining the membrane's electric potential. These ion channels are present in many various biological systems. They frequently play a role in regulation of cellular level processes, many of these processes including muscle relaxation, hypertension, insulin secretion etc. [7] Some examples of potassium ion channels within biological systems include K ...
The Goldman–Hodgkin–Katz flux equation (or GHK flux equation or GHK current density equation) describes the ionic flux across a cell membrane as a function of the transmembrane potential and the concentrations of the ion inside and outside of the cell.
The maintenance of these concentration gradients requires active transport of ionic species. The sodium-potassium and sodium-calcium exchangers are the best known of these. Some of the basic properties of the Na/Ca exchanger have already been well-established: the stoichiometry of exchange is 3 Na + : 1 Ca 2+ and the exchanger is electrogenic ...
Developmental bioelectricity is a sub-discipline of biology, related to, but distinct from, neurophysiology and bioelectromagnetics.Developmental bioelectricity refers to the endogenous ion fluxes, transmembrane and transepithelial voltage gradients, and electric currents and fields produced and sustained in living cells and tissues.
The concept of Hofmeister ionicity I h has been invoked by Dharma-wardana et al. [21] where it is proposed to define I h as a sum over all ionic species, of the product of the ionic concentration (mole fraction) and a fractional number specifying the "Hofmeister strength" of the ion in denaturing a given reference protein.
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An animated representation of the molecular structure of a simple ion channel. In electrophysiology, the term gating refers to the opening or closing (by deactivation or inactivation) of ion channels. [1]