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  2. Cardiac amyloidosis - Wikipedia

    en.wikipedia.org/wiki/Cardiac_amyloidosis

    Similar to the other subtypes of cardiac amyloidosis, a biopsy is required for diagnosis. [4] However, formal diagnosis of Senile cardiac amyloidosis is a diagnosis of exclusion. [4] Biopsy with histological evaluation can rule out Light chain and Familial subtypes, leaving the diagnosis of Senile. [4] This type is often misdiagnosed.

  3. Amyloidosis - Wikipedia

    en.wikipedia.org/wiki/Amyloidosis

    Amyloidosis has a combined estimated prevalence of 30 per 100,000 persons with the three most common forms being AL, ATTR, and AA. [49] The median age at diagnosis is 64. [11] AL has the highest incidence at approximately 12 cases per million persons per year and an estimated prevalence of 30,000 to 45,000 cases in the US and European Union ...

  4. Amyloid cardiomyopathy - Wikipedia

    en.wikipedia.org/wiki/Amyloid_cardiomyopathy

    Amyloid cardiomyopathy (stiff heart syndrome) [5] is a condition resulting in the death of part of the myocardium (heart muscle). It is associated with the systemic production and release of many amyloidogenic proteins , especially immunoglobulin light chain or transthyretin (TTR). [ 6 ]

  5. Wild-type transthyretin amyloid - Wikipedia

    en.wikipedia.org/.../Wild-Type_Transthyretin_Amyloid

    Wild-type transthyretin amyloid (WTTA), also known as senile systemic amyloidosis (SSA), [1] is a disease that typically affects the heart and tendons of elderly people. It is caused by the accumulation of a wild-type (that is to say a normal ) protein called transthyretin .

  6. AL amyloidosis - Wikipedia

    en.wikipedia.org/wiki/AL_amyloidosis

    AL amyloidosis is caused by the deposition of abnormal antibody free light chains. The abnormal light chains are produced by monoclonal plasma cells, and, although AL amyloidosis can occur without diagnosis of another disorder, it is often associated with other plasma cell disorders, such as multiple myeloma and Waldenström's macroglobulinemia. [6]

  7. AA amyloidosis - Wikipedia

    en.wikipedia.org/wiki/AA_amyloidosis

    AA amyloidosis is a form of amyloidosis, a disease characterized by the abnormal deposition of fibers of insoluble protein in the extracellular space of various tissues and organs. In AA amyloidosis, the deposited protein is serum amyloid A protein (SAA), an acute-phase protein which is normally soluble and whose plasma concentration is highest ...

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