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In 1868, French neurologist Jean-Martin Charcot first characterized the distinction between MS, with its resulting intention tremor, and the resting tremor characteristic of Parkinson's disease. Intention tremor became known as part of Charcot's triad [citation needed] (not to be confused with the Charcot triad of acute cholangitis), which ...
In the management of Parkinson's disease, due to the chronic nature of Parkinson's disease (PD), a broad-based program is needed that includes patient and family education, support-group services, general wellness maintenance, exercise, and nutrition. At present, no cure for the disease is known, but medications or surgery can provide relief ...
Parkinson's Disease causes constipation and gastric dysmotility that is severe enough to endanger comfort and even health. [26] A factor in this is the appearance of Lewy bodies and Lewy neurites even before these affect the functioning of the substantia nigra in the neurons in the enteric nervous system that control gut functions. [27]
Parkinsonism is a clinical syndrome characterized by tremor, bradykinesia (slowed movements), rigidity, and postural instability. [1] [2] Both hypokinetic (bradykinesia and akinesia) as well as hyperkinetic (cogwheel rigidity and tremors at rest) features are displayed by Parkinsonism. [3]
Resting tremor is the most common, but kinetic tremors—occurring during voluntary movements—and postural tremor—preventing upright, stable posture—also occur. [19] Tremor largely affects the hands and feet: [ 19 ] a classic parkinsonian tremor is " pill-rolling ", a resting tremor in which the thumb and index finger make contact in a ...
Parkinson-plus syndromes are usually more rapidly progressive and less likely to respond to antiparkinsonian medication than PD. [10] [11] However, the additional features of the diseases may respond to medications not used in PD. [citation needed] Current therapy for Parkinson-plus syndromes is centered around a multidisciplinary treatment of ...
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