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The Wassermann test or Wassermann reaction (WR) [1] is an antibody test for syphilis, named after the bacteriologist August Paul von Wassermann, based on complement fixation. It was the first blood test for syphilis and the first in the nontreponemal test (NTT) category. Newer NTTs, such as the RPR and VDRL tests, have mostly replaced it.
The rapid plasma reagin test (RPR test or RPR titer) is a type of rapid diagnostic test that looks for non-specific antibodies in the blood of the patient that may indicate an infection by syphilis or related non-venereal treponematoses. It is one of several nontreponemal tests for syphilis (along with the Wassermann test and the VDRL test).
Syphilis is typically spread through direct contact with a syphilis sore, known as a chancre, during vaginal, anal or oral sex. It can also be passed from a pregnant person to a child during birth.
Jarisch–Herxheimer reaction in a person with syphilis and human immunodeficiency virus [71] One of the potential side effects of treatment is the Jarisch–Herxheimer reaction. [3] It frequently starts within one hour and lasts for 24 hours, with symptoms of fever, muscle pains, headache, and a fast heart rate. [3]
(Reuters) -The U.S. Food and Drug Administration on Friday granted marketing authorization to the first at-home, over-the-counter test to detect syphilis antibodies in human blood in a move that ...
It’s not common for people to develop tertiary syphilis, but this stage can be serious. It can affect the heart, blood vessels, brain and nervous system. It can even be deadly.
Centers for Disease Control and Prevention (CDC)-approved standard tests include the VDRL test (a slide test), the rapid plasma reagin (RPR) test (a card test), the unheated serum reagin (USR) test, and the toluidine red unheated serum test (TRUST). [2] These have mostly replaced the first nontreponemal test, the Wassermann test. [citation needed]
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