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A paraganglioma is a rare neuroendocrine neoplasm that may develop at various body sites (including the head, neck, thorax and abdomen). When the same type of tumor is found in the adrenal gland, they are referred to as a pheochromocytoma. They are rare tumors, with an overall estimated incidence of 1 in 300,000. [1]
In the cases with underlying tumors, benign lesions including adrenal cyst and myelolipoma bigger than 10 cm may spontaneously bleed into the adrenal gland or retroperitoneum. Massive bleeding from a primary adrenal tumor could be fatal in up to half of the reported cases, which are most resulted from pheochromocytoma. [14]
Likelihood of diagnosis when an adrenal-nodule is identified; pheochromocytoma is in yellow near the top-right corner. Classically, the pheochromocytoma "rules of 10" have been taught, particularly to medical students: [177] 10% of patients have malignant disease; 10% of patients have bilateral (both left and right adrenal glands) disease
The indications to do FNAC are: nodules more than 1 cm with two ultrasound criteria suggestive of malignancy, nodules of any size with extracapsular extension or lymph nodes enlargement with unknown source, any sizes of nodules with history of head and neck radiation, family history of thyroid carcinoma in two or more first degree relatives ...
Calcinosis cutis can range in intensity from little nodules in one area of the body to huge, crippling lesions affecting a vast portion of the body. [1] Five kinds of the condition are typically distinguished: calciphylaxis , idiopathic calcification, iatrogenic calcification, dystrophic calcification, and metastatic calcification.
An accessory spleen is a small nodule of splenic tissue found apart from the main body of the spleen. Accessory spleens are found in approximately 10 percent of the population [1] and are typically around 1 centimetre in diameter. They may resemble a lymph node or a small spleen. They form either by the result of developmental anomalies or ...
In the photo, an apparent field defect in this segment of a colon has generated four polyps (labeled with the size of the polyps, 6mm, 5mm, and two of 3mm, and a cancer about 3 cm across in its longest dimension). These neoplasms are also indicated, in the diagram below the photo, by 4 small tan circles (polyps) and a larger red area (cancer).
[9] [10] Symptoms may include fever, night sweats, and weight loss. [2] Often, nonpainful enlarged lymph nodes occur in the neck, under the arm, or in the groin. [2] Persons affected may feel tired or be itchy. [2] The two major types of Hodgkin lymphoma are classic Hodgkin lymphoma and nodular lymphocyte-predominant Hodgkin lymphoma. [5]