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  2. Tamoxifen - Wikipedia

    en.wikipedia.org/wiki/Tamoxifen

    The effects of tamoxifen on breast cancer Ki-67 expression, sex hormone-binding globulin (SHBG) levels, and IGF-1 levels are dose-dependent across a dosage range of 1 to 20 mg/day in women with breast cancer. [84] Tamoxifen has been found to decrease insulin-like growth factor 1 (IGF-1) levels by 17 to 38% in women and men. [85]

  3. Toremifene - Wikipedia

    en.wikipedia.org/wiki/Toremifene

    The side effects of toremifene are similar to those of tamoxifen. [5] The most common side effect is hot flashes. [5] Other side effects include sweating, nausea, vomiting, dizziness, vaginal discharge, and vaginal bleeding. [5] [7] In women with bone metastases, hypercalcemia may occur. [5] Toremifene has a small risk of thromboembolic events. [5]

  4. Breast cancer management - Wikipedia

    en.wikipedia.org/wiki/Breast_cancer_management

    Staging breast cancer is the initial step to help physicians determine the most appropriate course of treatment. As of 2016, guidelines incorporated biologic factors, such as tumor grade, cellular proliferation rate, estrogen and progesterone receptor expression, human epidermal growth factor 2 (HER2) expression, and gene expression profiling into the staging system.

  5. Exemestane - Wikipedia

    en.wikipedia.org/wiki/Exemestane

    Oral exemestane 25 mg/day for 2–3 years of adjuvant therapy was generally more effective than 5 years of continuous adjuvant tamoxifen in the treatment of postmenopausal women with early-stage estrogen receptor-positive/unknown receptor status breast in a large well-designed [citation needed] trial. Preliminary data from the open-label TEAM ...

  6. Selective estrogen receptor modulator - Wikipedia

    en.wikipedia.org/wiki/Selective_estrogen...

    The hydroxyl group is of particular importance for ER binding of 4-hydroxytamoxifen, and the ethyl side chain of tamoxifen protrudes out of the ligand-binding domain of the ER. [27] Few tamoxifen users have had increased rates of uterine cancer, hot flushes, and thromboembolisms. The drug can also cause hepatocarcinomas in rats.

  7. Cialis Side Effects: What to Expect (& How to Avoid Them) - AOL

    www.aol.com/cialis-side-effects-expect-avoid...

    Tadalafil 20-milligram side effects are often more noticeable than 10-milligram or 5-milligram side effects when it comes to acid reflux and indigestion. Adjusting your dosage might help keep the ...

  8. Study of Tamoxifen and Raloxifene - Wikipedia

    en.wikipedia.org/wiki/Study_of_Tamoxifen_and...

    One of the largest breast cancer prevention studies ever, [2] it included 22,000 women in 400 medical centers in the United States and Canada. [3] [4] [5]The study concluded that raloxifene caused fewer side-effects and less endometrial cancer than tamoxifen.

  9. How to Pay the Lowest Price for Cialis & Tadalafil - AOL

    www.aol.com/lifestyle/pay-lowest-price-cialis...

    Costs depend on your prescribed dosage and whether you go with brand-name Cialis or the more affordable generic version of tadalafil. Brand-name Cialis can be pricey when used frequently.

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