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Probenecid, also sold under the brand name Probalan, is a medication that increases uric acid excretion in the urine. It is primarily used in treating gout and hyperuricemia . Probenecid was developed as an alternative to caronamide [ 1 ] to competitively inhibit renal excretion of some drugs, thereby increasing their plasma concentration and ...
Sulopenem/probenecid, sold under the brand name Orlynvah, is a fixed-dose combination medication used for the treatment of urinary tract infections. [1] It contains sulopenem , a penem antibacterial , as the prodrug sulopenem etzadroxil; and probenecid , a renal tubular transport inhibitor .
Sulopenem (CP-70,429) is a thiopenem antibiotic derivative from the penem family, which unlike most related drugs is orally active. It was developed in Japan in the 1990s, and has been approved to treat uncomplicated urinary tract infections in combination with probenecid (Brand name: Orlynvah).
Adults over 65 should get the pneumococcal vaccine, which protects against pneumococcal disease caused by bacteria, Dr. Kavasery says. These diseases include pneumonia, ear infections, sinus ...
New drugs to treat debilitating menopause symptoms — namely hot flashes — are finally on the market or are in development. But doctors say insurance companies either won’t pay for them or ...
It is, however, not recommended if a person has a history of kidney stones. [75] Probenecid can be used in a combined therapy with allopurinol is more effective than allopurinol monotherapy. [76] [77] [78] Pegloticase is an option for the 3% of people who are intolerant to other medications. [79] It is a third line agent. [64]
Ertapenem is mainly eliminated via the kidneys and urine (80%) and to a minor extent via the faeces (10%). Of the 80% found in the urine, 38% is excreted as the parent drug and 37% as the ring-opened metabolite. The biological half-life is about 3.5 hours in women, 4.2 hours in men and 2.5 hours in children up to 12 years of age. [7] [13]
It’s a community-based program that matches volunteers over 50, as literacy tutors, with struggling students. “The older adults go to the school and work with kids on projects.