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  2. Probenecid - Wikipedia

    en.wikipedia.org/wiki/Probenecid

    Probenecid, also sold under the brand name Probalan, is a medication that increases uric acid excretion in the urine. It is primarily used in treating gout and hyperuricemia . Probenecid was developed as an alternative to caronamide [ 1 ] to competitively inhibit renal excretion of some drugs, thereby increasing their plasma concentration and ...

  3. Sulopenem/probenecid - Wikipedia

    en.wikipedia.org/wiki/Sulopenem/probenecid

    Sulopenem/probenecid, sold under the brand name Orlynvah, is a fixed-dose combination medication used for the treatment of urinary tract infections. [1] It contains sulopenem , a penem antibacterial , as the prodrug sulopenem etzadroxil; and probenecid , a renal tubular transport inhibitor .

  4. Gout - Wikipedia

    en.wikipedia.org/wiki/Gout

    It is, however, not recommended if a person has a history of kidney stones. [75] Probenecid can be used in a combined therapy with allopurinol is more effective than allopurinol monotherapy. [76] [77] [78] Pegloticase is an option for the 3% of people who are intolerant to other medications. [79] It is a third line agent. [64]

  5. Sulopenem - Wikipedia

    en.wikipedia.org/wiki/Sulopenem

    Sulopenem (CP-70,429) is a thiopenem antibiotic derivative from the penem family, which unlike most related drugs is orally active. It was developed in Japan in the 1990s, and has been approved to treat uncomplicated urinary tract infections in combination with probenecid (Brand name: Orlynvah).

  6. Tophus - Wikipedia

    en.wikipedia.org/wiki/Tophus

    A tophus (Latin: "stone", pl.: tophi) is a deposit of monosodium urate crystals, in people with longstanding high levels of uric acid (urate) in the blood, a condition known as hyperuricemia. Tophi are pathognomonic for the disease gout. Most people with tophi have had previous attacks of acute arthritis, eventually leading to the formation of ...

  7. Sulfonamide (medicine) - Wikipedia

    en.wikipedia.org/wiki/Sulfonamide_(medicine)

    Prontosil, as Bayer named the new drug, was the first medicine ever discovered that could effectively treat a range of bacterial infections inside the body. It had a strong protective action against infections caused by streptococci , including blood infections, childbed fever , and erysipelas , and a lesser effect on infections caused by other ...

  8. These Are the 6 Vaccines Doctors Are Begging Everyone Over 50 ...

    www.aol.com/6-vaccines-doctors-begging-everyone...

    Adults over 65 should get the pneumococcal vaccine, which protects against pneumococcal disease caused by bacteria, Dr. Kavasery says. These diseases include pneumonia, ear infections, sinus ...

  9. Nonsteroidal anti-inflammatory drug - Wikipedia

    en.wikipedia.org/wiki/Nonsteroidal_anti...

    For people over the age of 65 years old, the balance between the benefits of pain-relief medications such as NSAIDS and the potential for adverse effects has not been well determined. [50] There is some evidence suggesting that, for some people, use of NSAIDs (or other anti-inflammatories) may contribute to the initiation of chronic pain. [51]

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