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The definition of a COPD exacerbation is commonly described as "lost in translation", [9] meaning that there is no universally accepted standard with regard to defining an acute exacerbation of COPD. Many organizations consider it a priority to create such a standard, as it would be a major step forward in the diagnosis and quality of treatment ...
Chronic obstructive pulmonary disease (COPD) is a type of progressive lung disease characterized by chronic respiratory symptoms and airflow limitation. [8] GOLD 2024 defined COPD as a heterogeneous lung condition characterized by chronic respiratory symptoms (dyspnea or shortness of breath, cough, sputum production or exacerbations) due to abnormalities of the airways (bronchitis ...
Paroxysmal nocturnal dyspnea is a common symptom of several heart conditions such as heart failure with preserved ejection fraction, in addition to asthma, chronic obstructive pulmonary disease, and sleep apnea. [8] Other symptoms that may be seen alongside paroxysmal nocturnal dyspnea are weakness, orthopnea, edema, fatigue, and dyspnea. [9]
When chronic bronchitis occurs together with decreased airflow it is known as chronic obstructive pulmonary disease (COPD). [27] [26] Many people with chronic bronchitis have COPD; however, most people with COPD do not also have chronic bronchitis. [10] [28] Estimates of the number of people with COPD who have chronic bronchitis are 7–40%.
In 1968 Andor Szentivanyi first described The Beta Adrenergic Theory of Asthma; in which blockage of the Beta-2 receptors of pulmonary smooth muscle cells causes asthma. [27] Szentivanyi's Beta Adrenergic Theory is a citation classic [ 28 ] using the Science Citation Index and has been cited more times than any other article in the history of ...
Specifically, clinical characteristics such as allergy and bronchial hyperresponsiveness that are commonly observed in individuals afflicted with asthma were viewed as likely determinants of the life-threatening disease, COPD (in the Netherlands, the term chronic non-specific lung disease was adopted as an umbrella term for asthma and COPD).
Asthma phenotyping and endotyping has emerged as a novel approach to asthma classification inspired by precision medicine which separates the clinical presentations of asthma, or asthma phenotypes, from their underlying causes, or asthma endotypes. The best-supported endotypic distinction is the type 2-high/type 2-low distinction.
Ascension Saint Thomas is a faith-based, non-profit health system in Middle Tennessee, with a 125-year history in the area.. Today, the health system offers a comprehensive system of care, with more than 250 sites of care that cover a 45-county area in Tennessee consisting of 16 hospitals and a network of affiliated joint ventures, medical practices, clinics and specialty facilities.